DRY EYE DISEASE (DED)

This study tests whether injecting stem cells into the eye can help people with severe dry eye caused by graft-versus-host disease (GVHD), a complication of bone marrow transplants. About 30 adults who have not responded to standard treatments will receive either one or two doses…

This study tests a disc made from donated placenta tissue to see if it can heal the eye's surface better than standard drops in people with moderate to severe dry eye. About 40 adults who haven't gotten enough relief from artificial tears will take part. The disc is placed in the…

This study compares two approved cyclosporine eye drops (Vevye® and a generic) to see which one better increases mucus-producing cells in the eyes of people with dry eye disease. Sixty adults will use the drops daily for 8 weeks and have eye exams every 2 weeks. The goal is to fi…

This study tests a small device that attaches to a smartphone to help diagnose dry eye disease. It takes special pictures of the eye's surface using different lights. The goal is to see if people can use it at home to get accurate results, compared to a standard eye exam. About 5…

This study tests a new eye drop called BRM421 in 99 adults with dry eye disease. It compares BRM421 to standard artificial tears over 6 weeks to see if it is safer and more effective at reducing eye damage and discomfort. The goal is to find a better way to ease dry eye symptoms.

This study compares two behavioral interventions—Baduanjin exercise or laughter therapy combined with artificial tears—against artificial tears alone for treating dry eye disease. About 540 adults aged 18 to 45 with dry eye will participate for 12 weeks, with follow-ups up to 48 …

This study compares two eye drop treatments, rebamipide and diquafosol, for managing dry eye disease in people having cataract surgery. About 60 adults with mild to moderate dry eye will use one of the drops for one month before and three months after surgery. The goal is to see …

This study tests whether VMX eye drops can improve tear film stability and reduce symptoms in people with mild to moderate dry eye disease. About 76 adults will receive either VMX drops or standard treatment, and researchers will measure changes in tear quality and comfort. The g…

This study tests whether the drug acoltremon can improve dry eye symptoms in real-world settings. Researchers will enroll 60 adults with dry eye disease and track their symptoms using surveys over three months. The goal is to see if acoltremon offers meaningful relief beyond curr…

This study tests if a structured blinking exercise can reduce dry eye symptoms in adults with glaucoma who use daily eye drops. Over two weeks, participants will do special blink cycles three times a day. Researchers will measure symptom relief and tear film health, comparing gla…

This study tests whether eyedrops made from Kelulut (stingless bee) honey are safe and can ease dry eye symptoms. About 45 adults will use the drops three times a day for one month, while continuing their usual treatments. Researchers will check tear stability and eye comfort at …

This study tests a disposable moisture chamber worn over glasses for 2 hours in 35 adults with mild to moderate dry eye disease. Researchers will measure tear film stability, tear volume, and symptom scores before and after wear to see if the device provides short-term relief.

This study tests whether a new eye drop called DFL24498 can safely reduce the signs and symptoms of dry eye disease. About 417 adults with dry eye will use either the study drop or a placebo drop for 12 weeks. Researchers will measure changes in eye surface staining and dryness s…

This study looks at whether a special cyclosporin eye drop (Vevizye) can reduce eye dryness and redness in people with moderate to severe dry eye disease. It includes 25 adults who have not gotten enough relief from artificial tears. The main goal is to see if symptoms improve af…

This study looks at whether dry eye disease makes it harder to calculate the right lens power before cataract surgery. About 100 adults aged 40 and older who need cataract surgery will take part. Researchers will compare the accuracy of lens power calculations between people with…