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Stem cells aim to soothe dry eyes in transplant patients

NCT ID NCT06905834

Not yet recruiting Disease control Sponsor: Instituto de Investigación Biomédica de Salamanca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether injecting stem cells into the eye can help people with severe dry eye caused by graft-versus-host disease (GVHD), a complication of bone marrow transplants. The trial will include 30 adults who have not improved with standard treatments. Participants will receive either a low or high dose of stem cells, and researchers will measure changes in eye surface health, tear production, and symptoms over time.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
mesenchymal stem cells (from donor fat tissue)
What this could lead to
If it works, this could offer a new treatment option for severe dry eye in GVHD patients who haven't responded to standard therapies.
What could go wrong
This is a small, early-phase trial (30 people) testing safety and effectiveness. The treatment may not work for everyone, and side effects from the injection or cells are possible.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome graft versus host disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE DISEASE (DED) GRAFT-VERSUS-HOST DISEASE (GVHD)

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

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