New eye drops aim to soothe dry eye sufferers
NCT ID NCT07503886
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new eye drop called DFL24498 in people with dry eye disease. About 417 adults will use the drops four times a day for 12 weeks. Researchers will check if the drops improve eye surface health and reduce dryness symptoms compared to a placebo.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- DFL24498 eye drops
- What this could lead to
- If successful, this could lead to a new prescription eye drop that reduces dry eye symptoms and eye surface damage.
- What could go wrong
- This is an early Phase 2 trial, so the drops may not work better than placebo. Side effects are possible, and results may not apply to all dry eye patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Alpine Research Organization, Inc.
NOT_YET_RECRUITINGClinton, Utah, 84015, United States
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Arizona Eye Center
RECRUITINGChandler, Arizona, 85224, United States
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Asheville Eye Associates - Regional Medical Park
NOT_YET_RECRUITINGAsheville, North Carolina, 28803, United States
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Canyon City Eyecare
RECRUITINGAzusa, California, 91702, United States
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Cincinnati Eye Institute
NOT_YET_RECRUITINGMason, Ohio, 45040, United States
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Clayton Eye Clinical Research
RECRUITINGMorrow, Georgia, 30260, United States
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Comprehensive Eye Care, Ltd.
NOT_YET_RECRUITINGWashington, Missouri, 63090, United States
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Core, Inc.
NOT_YET_RECRUITINGShelby, North Carolina, 28150, United States
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Eye Research Foundation
RECRUITINGNewport Beach, California, 92663, United States
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Global Research Management, Inc.
RECRUITINGGlendale, California, 91204, United States
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Houston Eye Associates
NOT_YET_RECRUITINGHouston, Texas, 77025, United States
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Lake Travis Eye and Laser Center
RECRUITINGLakeway, Texas, 78738, United States
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LoBue Laser and Eye Medical Center
NOT_YET_RECRUITINGMurrieta, California, 82562, United States
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Minnesota Eye Consultants
NOT_YET_RECRUITINGMinnetonka, Minnesota, 55305, United States
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NVision Clinical Research, LLC
RECRUITINGTorrance, California, 90505, United States
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Oculus Research, Inc.
RECRUITINGGarner, North Carolina, 27529, United States
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Piedmont Eye Center
RECRUITINGLynchburg, Virginia, 24502, United States
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Price Vision Group / Cornea Research Foundation of America
RECRUITINGIndianapolis, Indiana, 46260, United States
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Scott & Christie and Associates, PC
RECRUITINGCranberry Township, Pennsylvania, 16066, United States
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Shettle Eye Research, Inc.
NOT_YET_RECRUITINGLargo, Florida, 33773, United States
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Tekwani Vision Center
NOT_YET_RECRUITINGSt Louis, Missouri, 63128, United States
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Total Eye Care, PA - Memphis
RECRUITINGMemphis, Tennessee, 38119, United States
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United Medical Research Institute
RECRUITINGInglewood, California, 90301, United States
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University of South Florida - Marshall Student Center
NOT_YET_RECRUITINGTampa, Florida, 33612, United States
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