New eye drops aim to soothe dry eye sufferers

NCT ID NCT07503886

Recruiting now Symptom relief Sponsor: Dompé Farmaceutici S.p.A Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new eye drop called DFL24498 in people with dry eye disease. About 417 adults will use the drops four times a day for 12 weeks. Researchers will check if the drops improve eye surface health and reduce dryness symptoms compared to a placebo.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

DFL24498 eye drops

What this could lead to

If successful, this could lead to a new prescription eye drop that reduces dry eye symptoms and eye surface damage.

What could go wrong

This is an early Phase 2 trial, so the drops may not work better than placebo. Side effects are possible, and results may not apply to all dry eye patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

dry eye syndrome xerophthalmia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

DRY EYE DISEASE (DED)

Contacts and locations

Show contact details

Study contacts

Contact

Phone: •••-•••-••••

Locations

Alpine Research Organization, Inc.
NOT_YET_RECRUITING

Clinton, Utah, 84015, United States
Arizona Eye Center
RECRUITING

Chandler, Arizona, 85224, United States
Asheville Eye Associates - Regional Medical Park
NOT_YET_RECRUITING

Asheville, North Carolina, 28803, United States
Canyon City Eyecare
RECRUITING

Azusa, California, 91702, United States
Cincinnati Eye Institute
NOT_YET_RECRUITING

Mason, Ohio, 45040, United States
Clayton Eye Clinical Research
RECRUITING

Morrow, Georgia, 30260, United States
Comprehensive Eye Care, Ltd.
NOT_YET_RECRUITING

Washington, Missouri, 63090, United States
Core, Inc.
NOT_YET_RECRUITING

Shelby, North Carolina, 28150, United States
Eye Research Foundation
RECRUITING

Newport Beach, California, 92663, United States
Global Research Management, Inc.
RECRUITING

Glendale, California, 91204, United States
Houston Eye Associates
NOT_YET_RECRUITING

Houston, Texas, 77025, United States
Lake Travis Eye and Laser Center
RECRUITING

Lakeway, Texas, 78738, United States
LoBue Laser and Eye Medical Center
NOT_YET_RECRUITING

Murrieta, California, 82562, United States
Minnesota Eye Consultants
NOT_YET_RECRUITING

Minnetonka, Minnesota, 55305, United States
NVision Clinical Research, LLC
RECRUITING

Torrance, California, 90505, United States
Oculus Research, Inc.
RECRUITING

Garner, North Carolina, 27529, United States
Piedmont Eye Center
RECRUITING

Lynchburg, Virginia, 24502, United States
Price Vision Group / Cornea Research Foundation of America
RECRUITING

Indianapolis, Indiana, 46260, United States
Scott & Christie and Associates, PC
RECRUITING

Cranberry Township, Pennsylvania, 16066, United States
Shettle Eye Research, Inc.
NOT_YET_RECRUITING

Largo, Florida, 33773, United States
Tekwani Vision Center
NOT_YET_RECRUITING

St Louis, Missouri, 63128, United States
Total Eye Care, PA - Memphis
RECRUITING

Memphis, Tennessee, 38119, United States
United Medical Research Institute
RECRUITING

Inglewood, California, 90301, United States
University of South Florida - Marshall Student Center
NOT_YET_RECRUITING

Tampa, Florida, 33612, United States