DEPRESSION, ANXIETY
Clinical trials for DEPRESSION, ANXIETY explained in plain language.
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Brain light treatment tested for depression relief
Disease control CompletedThis study tested whether a non-invasive light therapy, delivered through a headset to the forehead, could help reduce symptoms of major depression. Fifty adults with depression were randomly assigned to receive either real light treatment at different settings or a fake (sham) t…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: NeuroThera DE • Aim: Disease control
Last updated Mar 30, 2026 14:35 UTC
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New hope for foster Kids' mental health: custom program shows promise
Disease control CompletedThis study evaluated a parenting support program called KEEP, which was specially adapted for foster and kinship families from underserved communities. Researchers tested whether these tailored versions of the program could help reduce mental health problems like depression, anxi…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Oregon Social Learning Center • Aim: Disease control
Last updated Mar 17, 2026 12:55 UTC
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Savings groups and counseling aim to help kenyan families thrive with HIV
Disease control CompletedThis study tested a community program in Kenya designed to help people living with HIV. It combined a savings and loan group with education on parenting, business skills, and mental health therapy. The goal was to see if this support system could help people stick to their HIV me…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: The University of Texas Medical Branch, Galveston • Aim: Disease control
Last updated Mar 02, 2026 15:28 UTC
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Can a mobile chat program reduce HIV risk and boost mental health?
Prevention CompletedThis study tested whether a mobile chat counseling program could help reduce HIV risk and improve mental health for gay and bisexual men in Romania. 300 HIV-negative men at risk were randomly assigned to receive either eight weekly live chat sessions with a trained counselor or e…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Columbia University • Aim: Prevention
Last updated Mar 31, 2026 12:14 UTC
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App aims to boost 'Homework' between therapy sessions
Symptom relief CompletedThis study tested a simple, secure website called Adhere.ly, designed to help therapists give and track practice exercises (homework) to their clients between therapy sessions. It compared standard therapy for anxiety and depression to therapy that used this digital tool. The goa…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of South Florida • Aim: Symptom relief
Last updated Apr 02, 2026 04:12 UTC
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Surgery drug shows promise for Post-Op depression
Symptom relief CompletedThis study tested whether a single dose of ketamine given during surgery could reduce depression symptoms afterward. It involved 110 adults with moderate to severe depression who were having a specific brain shunt procedure. Researchers compared patients who received ketamine to …
Matched conditions: DEPRESSION, ANXIETY
Phase: PHASE4 • Sponsor: Benha University • Aim: Symptom relief
Last updated Apr 02, 2026 04:12 UTC
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Can online therapy ease gut troubles and anxiety?
Symptom relief CompletedThis study tested whether an online acceptance and commitment therapy (ACT) program is practical and helpful for people with gut-brain interaction disorders (like IBS) who also have anxiety or depression. Thirty Swedish adults tried the self-guided online sessions and gave feedba…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Örebro University, Sweden • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Virtual reality therapy trial aims to ease depression and anxiety
Symptom relief CompletedThis study tested a new online coaching program based on cognitive behavioral therapy, delivered either through immersive virtual reality or on a regular computer screen. Researchers compared these two methods against a group receiving no coaching to see which was most effective …
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of Southern California • Aim: Symptom relief
Last updated Apr 01, 2026 14:41 UTC
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Can a phone app ease the emotional burden for breast cancer survivors?
Symptom relief CompletedThis study tested whether a publicly available mobile app (IntelliCare) could help reduce depression and anxiety in breast cancer survivors. It involved 313 women diagnosed within the past five years who reported elevated symptoms. The research also explored if adding human coach…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: University of Virginia • Aim: Symptom relief
Last updated Mar 31, 2026 12:11 UTC
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New therapy aims to ease the heavy burden on cancer caregivers
Symptom relief CompletedThis study tested whether a short therapy program could help family members caring for cancer patients. Over 500 unpaid caregivers were randomly assigned to receive either a special problem-solving therapy or a general support session, in addition to their usual care. The goal wa…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Washington University School of Medicine • Aim: Symptom relief
Last updated Mar 23, 2026 15:18 UTC
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Can laughter be the best medicine for dialysis stress?
Symptom relief CompletedThis study tested whether laughter therapy could help people receiving hemodialysis treatment feel better. Researchers worked with 69 patients to see if group laughter sessions could reduce stress, anxiety, and depression while improving their quality of life. The therapy involve…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Zonguldak Bulent Ecevit University • Aim: Symptom relief
Last updated Mar 23, 2026 15:14 UTC
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Surgery mood boost? anesthetic drug tested for Pre-Op anxiety
Symptom relief CompletedThis study tested whether a single dose of esketamine, a drug related to the anesthetic ketamine, could help reduce anxiety and depression in patients before and after heart valve surgery. Researchers enrolled 142 adults undergoing this major surgery to see if the treatment impro…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Chinese PLA General Hospital • Aim: Symptom relief
Last updated Mar 20, 2026 14:47 UTC
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Virtual reality headsets calm transplant patients in ICU
Symptom relief CompletedThis study tested whether virtual reality therapy could prevent anxiety, depression, and PTSD in lung transplant patients recovering in the intensive care unit. Patients on the transplant waiting list used VR headsets to gradually experience simulated ICU sounds and environments,…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Assistance Publique Hopitaux De Marseille • Aim: Symptom relief
Last updated Mar 18, 2026 18:25 UTC
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Can an 8-Week online program quiet the ringing in your ears?
Symptom relief CompletedThis study tested two different 8-week online programs to help adults who are distressed by tinnitus, the perception of ringing or buzzing in the ears. Researchers compared an internet-based cognitive behavioral therapy (CBT) program, a mindfulness-based program, and a waiting li…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Vilnius University • Aim: Symptom relief
Last updated Mar 18, 2026 14:40 UTC
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Can an app ease your gut troubles? swedish researchers test digital therapy
Knowledge-focused CompletedThis small Swedish study tested whether an online therapy program is practical and acceptable for people with gut-brain disorders like IBS who also have anxiety or depression. 27 participants tried the self-guided digital sessions and gave feedback through interviews and question…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Örebro University, Sweden • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:12 UTC
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Chile's pain puzzle: major study tracks how hurt and stress connect
Knowledge-focused CompletedThis study followed over 2,300 adults in Chile for one year to understand how common chronic pain is and how it connects to mental health, loneliness, and work stress. Researchers called participants to track their pain levels, mood, sleep, and daily life impact over 12 months. T…
Matched conditions: DEPRESSION, ANXIETY
Sponsor: Pontificia Universidad Catolica de Chile • Aim: Knowledge-focused
Last updated Mar 31, 2026 12:11 UTC
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Cultural training aims to bridge gaps in mental health support
Knowledge-focused CompletedThis study tested a culturally grounded training program called First Face, designed to teach community members how to recognize and respond to mental health crises. Researchers surveyed 92 staff members at the Healing Lodge of the Seven Nations before, after, and three months af…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Cambridge Health Alliance • Aim: Knowledge-focused
Last updated Mar 25, 2026 14:08 UTC
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Cash for counseling: study tests if money motivates students to get therapy
Knowledge-focused CompletedThis study tested different ways to encourage college students in Chennai, India, to use free mental health services. Researchers wanted to see if telling students their screening results for depression/anxiety or offering cash for attending a first therapy session would make the…
Matched conditions: DEPRESSION, ANXIETY
Phase: NA • Sponsor: Massachusetts Institute of Technology • Aim: Knowledge-focused
Last updated Mar 19, 2026 14:56 UTC
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Massive study reveals how pandemic disrupted care for millions with chronic illness
Knowledge-focused CompletedThis study looked back at the health records of nearly 1 million Canadian adults to understand how the COVID-19 pandemic affected their regular care for long-term conditions like diabetes, heart failure, and depression. Researchers compared the number of doctor visits, tests, and…
Matched conditions: DEPRESSION, ANXIETY
Sponsor: McMaster University • Aim: Knowledge-focused
Last updated Feb 25, 2026 15:07 UTC