DEPRESSION, ANXIETY

This study tests whether a short, modified exposure therapy given soon after rape can prevent post-traumatic stress disorder (PTSD) in women. About 166 women who have experienced sexual assault will be randomly assigned to either the brief therapy or standard care. The goal is to…

This study tests a free app called LightBEAM that offers videos, forums, and exercises to help parents manage stress, anxiety, and depression. About 300 Canadian parents of children aged 18 months to 9 years will use the app for 12 weeks. The goal is to see if the app improves pa…

This study tests a digital cognitive behavioral therapy program (SilverCloud) for Spanish-speaking adults with depression or anxiety. 426 participants will either use the program on their own or get extra support from a peer coach via phone or messaging. The goal is to see if add…

This study tests whether a physical activity program can help pregnant people with symptoms of depression or anxiety feel better. 88 participants will be given a step goal and wear an activity tracker. The program includes weekly reminders and motivational coaching every two week…

This trial aimed to test an online version of Acceptance and Commitment Therapy (ACT) for adults with disorders of gut-brain interaction (like IBS) who also have anxiety or depression. Participants would have been randomly assigned to either the ACT program or an online education…

This study tests a brief behavioral therapy program delivered via telehealth (STEP-UP) for children and teens aged 8 to 16 with anxiety or depression. Participants are recruited from community health centers and randomly assigned to either STEP-UP or a referral to local mental he…

This study tests a voice-assisted program using Amazon Alexa to help older adults (65+) with depression and their caregivers. Participants use the program for goal setting, reminders, and other mental health support over 12 weeks. Some participants also receive a guide to help th…

This study tests a mobile health system (smartwatch and app) combined with a week-long cycling event to help veterans reduce stress and PTSD symptoms. Thirty-six veterans will use the system for two months and participate in the cycling challenge. The goal is to see if this appro…

This study tests a remotely delivered 8-week program called ReStoreD for couples where one partner has had a stroke. The program teaches goal-setting, communication, and positive thinking skills to reduce anxiety and depression. Researchers will enroll 400 couples to see if the p…

This study is creating a large registry of 5,000 young people aged 8 to 20 who have depression or suicidal thoughts. Researchers will collect data from clinics across Texas to better understand these conditions and develop models to predict outcomes. The goal is to improve popula…

This study explores whether highlighting certain words in questionnaire instructions (like 'bothered by') affects how people with depression or anxiety respond. Two hundred U.S. adults who have been treated for these conditions in the past year will take the same survey twice in …

This study looks at whether a supplement made from black rice extract can increase levels of BDNF, a protein important for memory and mood. Researchers will give 12 healthy adults either the supplement or a placebo and measure BDNF in their blood. The goal is to see if this natur…

This study looks at how regular exercise influences sleep quality, chronotype (whether you're a morning or evening person), and depression symptoms in university students. Researchers will track 54 students from Aydın Adnan Menderes University who exercise regularly, using questi…