DEMENTIA WITH LEWY BODIES

This study tested a drug called CT1812 in 130 people with mild to moderate Dementia with Lewy Bodies. The goal was to see if the drug is safe and if it can help with symptoms like thinking and sleepiness. Participants received either the drug or a placebo for 6 months, and resear…

This study tested the drug nilotinib, already approved for leukemia, in 43 people with Dementia with Lewy Bodies (DLB). The main goal was to see if the drug is safe and tolerable in this group. Researchers also measured changes in brain proteins and amyloid plaques using spinal f…

This study tested whether the drug neflamapimod can help improve learning, memory, and problem-solving in people with dementia with Lewy bodies (DLB). 159 adults aged 55 and older with probable DLB took either the drug or a placebo. Researchers measured changes in thinking and da…

This study tested a dementia care program delivered by phone and web, where trained navigators (supervised by experts) helped patients and their caregivers. Over 1,200 people with dementia and their caregivers took part across six health systems. The goal was to see if this appro…

This study tested an online tool called WeCareAdvisor that helps caregivers of people with dementia manage difficult behaviors like aggression or wandering. 262 caregivers used the tool to see if it reduced their stress and boosted their confidence. The goal was to make daily car…

This study tested a virtual group therapy program called Cognitive Stimulation Therapy (V-CST) for people with mild to moderate dementia. 133 participants were randomly assigned to either join the online therapy or receive usual care. The goal was to see if the therapy could slow…

This study tested a special palliative care program for people with late-stage Alzheimer's or related dementias and their family caregivers. The program started during a hospital stay and included dementia-specific comfort care, caregiver education, and help with transitions. The…

This study involved 134 participants with Alzheimer's disease, frontotemporal degeneration, Lewy body dementia, or late-life psychiatric disorders. Researchers compared a new PET scan method that measures synaptic density with the standard FDG-PET scan to see which better disting…

This study surveyed 219 family caregivers of people with dementia to learn how swallowing difficulties (dysphagia) impact their daily lives and sense of burden. Caregivers completed a one-time online questionnaire about their loved one's swallowing issues, their own stress, and h…

This study examined 186 people with Alzheimer's, Lewy body, frontotemporal, or corticobasal dementia, plus healthy controls, to see if subtle brain signs (called neurological soft signs) differ between types. Participants had simple movement and coordination tests, along with mem…

This study tested whether a simple brain wave test (EEG) can help diagnose Alzheimer's disease at different stages. Researchers collected EEG data from 29 people, including those with mild memory problems, Alzheimer's, Lewy body dementia, and healthy volunteers. The goal was to s…

This study looked at how dementia with Lewy bodies (DLB) affects a person's sense of self, including memory and self-concept. Researchers compared 61 older adults with DLB, Alzheimer's disease, and healthy aging using memory tests and brain scans. The goal was to understand brain…

This study followed 378 people with moderate-to-severe Lewy body dementia and their caregivers for up to three years. Researchers used questionnaires and brief checkups to track symptoms, quality of life, and caregiver experiences as the disease progressed. The goal was to find c…

This study looked at how the brain and body communicate in people with conditions like autism, ADHD, Alzheimer's, and Parkinson's. Researchers measured signals from the brain, heart, and movements while participants did everyday activities like walking and slow breathing. The goa…