Cancer drug nilotinib tested for lewy body dementia in small trial

NCT ID NCT04002674

First seen Apr 04, 2026 · Last updated May 13, 2026 · Updated 4 times

Summary

This study tested the drug nilotinib, already approved for leukemia, in 43 people with Dementia with Lewy Bodies (DLB). The main goal was to see if the drug is safe and tolerable in this group. Researchers also measured changes in brain proteins and amyloid plaques using spinal fluid and PET scans. The trial was completed and double-blind, meaning neither patients nor doctors knew who got the real drug.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for DEMENTIA WITH LEWY BODIES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Contacts and locations

Locations

  • MedStar Georgetown University Hospital

    Washington D.C., District of Columbia, 20007, United States

Conditions

Explore the condition pages connected to this study.