CYSTIC FIBROSIS
Clinical trials for CYSTIC FIBROSIS explained in plain language.
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Can a common blood pressure drug help CF lungs clear mucus?
Disease control OngoingThis study tests whether losartan, a blood pressure medication, can help clear mucus from the lungs of people with cystic fibrosis (CF) who cannot take current CFTR-targeted therapies. Sixteen adults with mild to moderate lung disease will take losartan for over 12 weeks. The goa…
Matched conditions: CYSTIC FIBROSIS
Phase: EARLY_PHASE1 • Sponsor: University of Kansas Medical Center • Aim: Disease control
Last updated Apr 29, 2026 00:50 UTC
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Scientists hunt for genes that make CF lung disease worse or milder
Knowledge-focused OngoingThis study looks at how different genes can change the severity of lung disease in people with cystic fibrosis. Researchers will study 600 people with CF to find genetic clues. No treatment is given—this is an observation-only study.
Matched conditions: CYSTIC FIBROSIS
Sponsor: University of North Carolina, Chapel Hill • Aim: Knowledge-focused
Last updated Apr 29, 2026 00:35 UTC
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Tiny mouth bug may warn of lung danger in kids with CF
Knowledge-focused OngoingThis study follows 70 infants with cystic fibrosis to see if a germ called Porphyromonas catoniae, measured at 12 months old, can predict if they will get a serious lung infection with Pseudomonas aeruginosa by age 3. Researchers collect spit and stool samples over time to track …
Matched conditions: CYSTIC FIBROSIS
Phase: NA • Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:15 UTC
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New study tracks lung function in pregnant women with cystic fibrosis on modern drugs
Knowledge-focused OngoingThis study follows 285 pregnant women with cystic fibrosis to see how their lung function changes during pregnancy and for two years after giving birth. Researchers compare women who take highly effective CFTR modulators with those who do not. The goal is to understand how these …
Matched conditions: CYSTIC FIBROSIS
Sponsor: Amalia Magaret • Aim: Knowledge-focused
Last updated Apr 28, 2026 13:02 UTC