Scientists hunt for hidden sources of lung infections in cystic fibrosis
NCT ID NCT05686837
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand how nontuberculous mycobacteria (NTM) spread among people with cystic fibrosis (CF). NTM infections are hard to treat and common in CF, but their sources are unclear. Researchers will track 100 participants with CF and NTM, testing dust and water in clinics and mapping home water sources. The goal is to find where infections come from and how to prevent them.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify how NTM infections spread in healthcare settings and homes, leading to better prevention strategies for people with cystic fibrosis.
- What could go wrong
- This is an observational study, not a treatment trial. It may not find clear transmission links, and results may not apply to all settings or patients.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Dell Children's Ascension
Austin, Texas, 78723, United States
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Johns Hopkins Cystic Fibrosis Center
Baltimore, Maryland, 21287, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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The University of Vermont Medical Center
Colchester, Vermont, 05446, United States
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UT Southwestern Medical Center
Dallas, Texas, 75309, United States
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UVA Health University Medical Center
Charlottesville, Virginia, 22908, United States
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UW Medical Center
Seattle, Washington, 98195, United States
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Other studies related to the condition(s) this trial covers.
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- Early use of powerful CF drugs may boost growth in young children
- Hands-On therapy may soothe cystic fibrosis pain without drugs