CYSTIC FIBROSIS
Clinical trials for CYSTIC FIBROSIS explained in plain language.
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Cystic fibrosis drug trial halted early – what we know
Disease control TerminatedThis study tested a drug called (R)-Roscovitine in adults with cystic fibrosis who also have a chronic lung infection with Pseudomonas aeruginosa. The goal was to see if increasing doses of the drug were safe. The study was terminated early, so results are limited.
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE2 • Sponsor: University Hospital, Brest • Aim: Disease control
Last updated Jun 16, 2026 12:48 UTC
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Cystic fibrosis drug trial halted early: what happened?
Disease control TerminatedThis early-stage trial tested whether glycerol phenylbutyrate (Ravicti) could improve chloride transport in the nasal cells of adults with cystic fibrosis. Sixteen participants took the drug or a placebo for up to 7 days. The study was terminated early, so results are limited.
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: National Jewish Health • Aim: Disease control
Last updated Jun 10, 2026 13:27 UTC
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Gene therapy inhaler for cystic fibrosis tested, but study stopped early
Disease control TerminatedThis study tested a single dose of an inhaled gene therapy called BI 3720931 in adults with cystic fibrosis who cannot use standard CFTR modulator drugs. The goal was to see if it was safe and could improve lung function. The study was stopped early after enrolling only 5 people,…
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1, PHASE2 • Sponsor: Boehringer Ingelheim • Aim: Disease control
Last updated Jun 08, 2026 13:07 UTC
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Can growth hormone help cystic fibrosis patients regain weight?
Symptom relief TerminatedThis early-stage study tested whether growth hormone can help adults with cystic fibrosis who are underweight gain weight and muscle. The goal was to improve nutrition, strength, and quality of life. Only 5 people were enrolled before the study was stopped early.
Matched conditions: CYSTIC FIBROSIS
Phase: PHASE1 • Sponsor: University of Massachusetts, Worcester • Aim: Symptom relief
Last updated May 18, 2026 12:04 UTC
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Cystic fibrosis study investigates hidden lung infections
Knowledge-focused TerminatedThis study aimed to find out how common non-tuberculous mycobacteria (NTM) infections are in people with cystic fibrosis in France. Researchers collected sputum samples and blood from 848 patients to compare culture tests with a newer serology (antibody) test. The goal was to bet…
Matched conditions: CYSTIC FIBROSIS
Sponsor: University Hospital, Brest • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:09 UTC
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CF gene repair study halted early: lab tests show promise but trial ends
Knowledge-focused TerminatedThis study aimed to see if a special molecule (oligonucleotide blocker) could fix the genetic glitch in cells from people with cystic fibrosis. Researchers planned to test this on cells from 16 patients aged 12 and older. The trial was terminated early, so results are limited to …
Matched conditions: CYSTIC FIBROSIS
Phase: NA • Sponsor: University Hospital, Montpellier • Aim: Knowledge-focused
Last updated Jun 09, 2026 12:07 UTC
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AI listens to lungs: new study analyzes breathing sounds in chronic disease patients
Knowledge-focused TerminatedThis study tested whether artificial intelligence could detect and classify abnormal lung sounds in people with cystic fibrosis, COPD, or pulmonary fibrosis. Researchers used an electronic stethoscope to record breathing sounds during routine checkups and analyzed them with AI. T…
Matched conditions: CYSTIC FIBROSIS
Sponsor: Groupe Hospitalier de la Region de Mulhouse et Sud Alsace • Aim: Knowledge-focused
Last updated Jun 08, 2026 13:04 UTC