Gene therapy inhaler for cystic fibrosis tested, but study stopped early

NCT ID NCT06515002

First seen Nov 01, 2025 · Last updated May 01, 2026 · Updated 23 times

Summary

This study tested a single dose of an inhaled gene therapy called BI 3720931 in adults with cystic fibrosis who cannot use standard CFTR modulator drugs. The goal was to see if it was safe and could improve lung function. The study was terminated early after enrolling only 5 participants, so results are limited.

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Contacts and locations

Locations

  • Hospital Universitari Vall d'Hebron

    Barcelona, 08035, Spain

  • Hôpital Gui de Chauliac

    Montpellier, 34295, France

  • Osp. Pediatrico Bambin Gesù

    Roma, 00165, Italy

  • Royal Brompton Hospital

    London, SW3 6JY, United Kingdom

  • Universitair Medisch Centrum Utrecht

    Utrecht, 3584 CX, Netherlands

Conditions

Explore the condition pages connected to this study.