Massive study tracks sweat changes in 5000 CF patients on new drugs
NCT ID NCT03350828
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looks at 5000 people with cystic fibrosis who are already taking approved CFTR modulator medicines. Researchers measure sweat chloride levels before and after treatment to see how the drugs affect the body. The goal is to better understand the link between sweat chloride changes and health outcomes.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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Children's Healthcare of Atlanta and Emory University
Atlanta, Georgia, 30322, United States
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Children's Hospital Colorado
Aurora, Colorado, 80045, United States
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Children's Hospital Medical Center of Akron
Akron, Ohio, 44308, United States
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Children's Hospital of Michigan
Detroit, Michigan, 48201, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Children's Hospital of Pittsburgh of UPMC
Pittsburgh, Pennsylvania, 15224, United States
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Children's Hospital of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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Children's Mercy Kansas City
Kansas City, Missouri, 64108, United States
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Childrens Hospital Los Angeles
Los Angeles, California, 90027, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Dartmouth Hitchcock Medical Center
Lebanon, New Hampshire, 03756, United States
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Emory University
Atlanta, Georgia, 30327, United States
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Helen DeVos Children's Hospital
Grand Rapids, Michigan, 49503, United States
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Hershey Medical Center Pennsylvania State University
Hershey, Pennsylvania, 17033, United States
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John Hopkins Hospital
Baltimore, Maryland, 21287, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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National Jewish Health
Denver, Colorado, 80206, United States
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Nationwide Children's Hospital
Columbus, Ohio, 43205, United States
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Nemours Children's Clinic - Pensacola
Pensacola, Florida, 32514, United States
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New York Medical College at Westchester Medical Center
Valhalla, New York, 10595, United States
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Oregon Health Sciences University
Portland, Oregon, 97239, United States
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Primary Children's Cystic Fibrosis Center
Salt Lake City, Utah, 84113, United States
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Rainbow Babies and Children's Hospital/University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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Riley Hospital for Children
Indianapolis, Indiana, 46202, United States
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SSM Health Cardinal Glennon Children's Hospital
St Louis, Missouri, 63104, United States
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Seattle Children's Hospital
Seattle, Washington, 98105, United States
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St. Louis Children's Hospital
St Louis, Missouri, 63110, United States
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The Children's Hospital Alabama, University of Alabama at Birmingham
Birmingham, Alabama, 35233, United States
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The Cystic Fibrosis Center of Western New York
Buffalo, New York, 14203, United States
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The Minnesota Cystic Fibrosis Center
Minneapolis, Minnesota, 55455, United States
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The Nemours Children's Clinic - Orlando
Orlando, Florida, 32827, United States
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Toledo Children's Hospital
Toledo, Ohio, 43606, United States
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University of Arkansas for Medical Sciences
Little Rock, Arkansas, 72205, United States
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University of California San Diego
La Jolla, California, 92093, United States
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University of Chicago
Chicago, Illinois, 60637, United States
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University of Florida
Gainesville, Florida, 32610, United States
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University of Kansas Medical Center
Kansas City, Kansas, 66160, United States
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University of Kentucky
Lexington, Kentucky, 40506, United States
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University of Michigan, Michigan Medicine
Ann Arbor, Michigan, 48109, United States
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University of North Carolina at Chapel Hill
Chapel Hill, North Carolina, 27517, United States
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University of Tennessee CF Care and Research Center
Memphis, Tennessee, 38103, United States
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University of Texas Southwestern / Children's Health
Dallas, Texas, 75207, United States
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University of Texas Southwestern Medical Center
Dallas, Texas, 75390, United States
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University of Washington Medical Center
Seattle, Washington, 98195, United States
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University of Wisconsin
Madison, Wisconsin, 53792, United States
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Vanderbilt Children's Hospital
Nashville, Tennessee, 37232, United States
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West Virginia University - Morgantown
Morgantown, West Virginia, 26506, United States
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Yale University School of Medicine
New Haven, Connecticut, 06520, United States
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Can a peer coach help young people take control of their chronic illness?
- Could a single antibiotic be enough for cystic fibrosis lung infections?
- Early use of powerful CF drugs may boost growth in young children
- Hands-On therapy may soothe cystic fibrosis pain without drugs
- Newborn screening study aims to catch rare diseases at birth
- Breath sniffing may reveal early clues to cystic fibrosis drug success