COLO-RECTAL CANCER

This study tests a new drug called MBRC-201 in people with advanced solid tumors (like prostate, breast, lung, colorectal, or pancreatic cancer) that have not responded to standard treatments. The goal is to find the best dose and see if it can shrink tumors or slow their growth.…

This study tests whether artificial intelligence (AI) can help surgeons better predict risks for people having surgery for colorectal cancer. About 1,200 patients across Denmark will be split into two groups: one where the surgeon uses standard methods to assess risk, and another…

This early-phase study tests a new drug called ALX2004 in people with advanced or metastatic solid tumors (lung, head and neck, colorectal, esophageal) that have not responded to standard treatments. ALX2004 is an antibody drug conjugate designed to deliver chemotherapy directly …

This study looks at people with lung, colorectal, or prostate cancer that has spread to up to 10 spots in the body. It compares starting treatment right away versus waiting 6 months to see which approach helps people live longer and maintain quality of life. About 800 participant…

This study is testing a new blood test (the Natera CRC Screening Test) to see how well it can detect colorectal cancer and advanced growths in people at average risk. About 25,000 adults aged 40 and older who are already planning a colonoscopy will provide blood samples. The resu…

This study is checking how well the Shield blood test performs when used a second time to screen for colorectal cancer in average-risk people aged 45 to 81. About 3,375 participants will take the Shield test and then have a colonoscopy to see how accurate the blood test is. The g…

This study is testing a blood test (called a liquid biopsy) to see how well it can find colorectal cancer, advanced polyps, and Lynch syndrome-related cancers early. Researchers will enroll 1,200 people who have had a colonoscopy and take a blood sample to compare the test result…

This study tests whether a special training program can help people with a permanent colostomy feel more confident in managing their stoma and daily life. Researchers will enroll 70 adults who have had colorectal surgery and now have a permanent colostomy. The goal is to see if t…

This study tests whether a smartphone app with animations and games helps people prepare better for a colonoscopy compared to standard written instructions. About 252 adults scheduled for a colonoscopy will be randomly assigned to one of two education methods. The goal is to see …

This study is building a platform to better understand a person's risk of developing cancer or having it come back. Researchers will analyze blood samples from 850 people with certain cancers to find genetic markers, immune system changes, and other biological clues. The goal is …

This study is testing a new single-port robotic system for colorectal surgeries, such as for cancer or rectal prolapse. The robot is already approved for other areas but hasn't been widely used in colorectal procedures. Researchers will enroll 25 adults to see if the approach is …

This pilot study works with staff at community health centers to identify and test ways to make colorectal cancer screening easier for patients. Researchers will hold group discussions and analyze health records to see what strategies work best. The goal is to increase screening …