COLO-RECTAL CANCER

This early-phase study tests whether adding Akkermansia probiotics to standard immunotherapy and chemotherapy can safely help patients with advanced colorectal cancer that hasn't responded to prior treatments. The trial enrolls 22 adults whose tumors are MSS/pMMR type, which typi…

This early-phase trial tests whether adding the CIMAvax-EGF vaccine to standard chemotherapy and targeted drugs can trigger an immune response against metastatic colorectal cancer. Only 2 participants with a specific gene type (RAS/BRAF wild-type) were enrolled. The main goal is …

This study tests whether combining spectral CT scans with a genetic test (MSI) can more accurately predict if colorectal cancer has spread to nearby lymph nodes. Researchers will compare the imaging results with actual tissue samples from surgery or biopsy. The goal is to improve…

This study looks at whether CT scans can be used instead of colonoscopies to screen for colon cancer. Researchers will compare how well each method finds polyps and cancer in 600 adults aged 50-70. If CT scans work just as well, it could offer a faster and less invasive screening…

This long-running study follows nearly 100,000 French women, mostly teachers, since 1990 to understand what factors influence their risk of cancer, heart disease, diabetes, and other major illnesses. Participants fill out questionnaires every few years about their lifestyle, medi…

This study looks at whether a special home care program helps people with a new stoma (a surgical opening on the belly) recover better after colorectal cancer surgery. About 98 adults who had a stoma created will get extra support and teaching to manage their stoma at home. The g…

This study tests whether a simple blood test that looks for tumor DNA can detect colorectal cancer coming back earlier than standard CT scans. About 359 people who had surgery for stage II or III colorectal cancer will be randomly assigned to either the blood test plus frequent P…

This study looks at whether helping people aged 40-49 with a family history of colon cancer make informed choices about screening leads to more colonoscopies. Participants either get standard care (direct referral for colonoscopy) or a shared decision-making session where they ca…

This study looks at people aged 45-74 who had a positive fecal immunochemical test (FIT) but a normal colonoscopy. Even with a clear colonoscopy, these individuals may still have a higher risk of colorectal cancer. The trial will compare two follow-up options after two years: ano…