CEREBROVASCULAR DISORDERS

This study is testing if an intravenous drug called Dimephosphon can help people recover better after a recent ischemic stroke. About 184 adults who had a stroke within the last 24-72 hours will receive either the drug or a placebo. Researchers will measure how well people recove…

This study is testing whether aggressively lowering blood pressure can slow the progression of white matter lesions (brain damage seen on MRI) in older adults who have memory complaints. It will enroll 820 participants aged 60-88 with high blood pressure and moderate brain change…

This early-stage study is testing whether inhaling nitric oxide gas is safe and feasible for patients undergoing emergency surgery to remove a blood clot from the brain after a stroke. The gas may help protect vulnerable brain tissue by improving blood flow to areas at risk of pe…

This study is testing a new medical device called the Supernova stent retriever for treating acute ischemic strokes caused by large blood clots. The device is designed to physically remove clots from blocked brain arteries to restore blood flow. Researchers will enroll 100 stroke…

This study is testing if a simple, non-invasive treatment can help people recover better after a life-threatening brain bleed caused by a burst aneurysm. The treatment involves repeatedly inflating and deflating a blood pressure cuff on the arm or leg, which may trigger the body'…

This study tests whether a live video call between paramedics on scene and a hospital neurologist can improve the accuracy of diagnosing a stroke before the patient arrives at the hospital. Faster and more accurate diagnosis in the ambulance could help get patients the right trea…

This study is testing a new type of stroke rehabilitation therapy. It combines an enhanced version of mirror therapy, which uses visual feedback, to help people recover movement in their arm and hand after a stroke. The goal is to see if this personalized approach works better th…

This study is testing new virtual and mixed reality systems designed to help people recover arm and hand function after a stroke. It compares these high-tech mirror therapy methods to the traditional version to see which is better at improving movement and daily independence. The…

This study aims to understand how the body's heart and blood vessels react to a brief, stressful mental task and how those reactions might be connected to the health of the brain's blood vessels. Researchers will measure heart rate, blood pressure, and brain scans in 450 healthy …

This study is creating a collection of blood and tissue samples from people undergoing procedures for stroke or other blood vessel problems in the brain. Researchers will study these samples to find biological markers that could explain why strokes happen and how the body respond…

This study aims to understand why some people with atrial fibrillation (AF, an irregular heartbeat) still have a stroke even while taking blood-thinning medication. Researchers will follow 500 stroke patients with AF for about a year, collecting blood samples and heart scan data.…

This study aims to understand how a specific protein (BD-tau) in the blood changes in the first 48 hours after a stroke. Researchers will take blood samples every hour from 100 patients who have just had a stroke to see exactly when this marker rises and stops rising. The goal is…