Midlife stress may reveal secrets of brain aging

NCT ID NCT06029348

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how brief mental stress affects heart function and brain health in 450 adults aged 40-60. Participants complete two sessions: one with stress tests and heart monitoring, another with brain scans and memory tests. The goal is to understand links between stress responses and early signs of brain aging, like white matter changes. No treatment is given; this is an observational study to gather knowledge.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Pittsburgh

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

    Contact

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