Could a simple gas help stroke patients? early trial launches

NCT ID NCT05871606

Recruiting now Symptom relief Sponsor: Wake Forest University Health Sciences Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests whether inhaled nitric oxide is safe for people having emergency clot removal after a stroke. It includes 36 adults with severe strokes. The main goal is to find the highest safe dose without causing brain bleeding.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: inhaled nitric oxide (iNO)
What this could lead to: If safe, this could point toward a new way to protect the brain during stroke treatment.
What could go wrong: This is a very early phase 1 safety trial with only 36 people. It may not show benefit, and there is a risk of bleeding in the brain.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

cerebrovascular disorder ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE CEREBROVASCULAR DISEASE CEREBROVASCULAR DISORDERS

Contacts and locations

Locations

Atrium Health
RECRUITING

Charlotte, North Carolina, 28204, United States
Carolinas Medical Center
RECRUITING

Charlotte, North Carolina, 28203, United States

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