CARCINOMA, NON-SMALL-CELL LUNG

This early-phase study aimed to test the safety, side effects, and best dose of an experimental drug called QEQ278 in adults with advanced solid tumors. It enrolled 30 participants with specific advanced cancers (lung, kidney, esophageal, or head/neck) that had progressed despite…

This early-stage study tested whether combining a new immunotherapy drug (sasanlimab) with other targeted cancer therapies was safe and effective for people with advanced non-small cell lung cancer. The trial involved 34 participants and was designed in two parts, testing differe…

This was an early-stage study to test the safety and initial effectiveness of a new drug, PF-07284890, for people with advanced cancers that have a specific genetic change called a BRAF V600 mutation. The trial included patients with cancers like melanoma and lung cancer, some of…

This study compared a new targeted drug called pralsetinib against standard chemotherapy for people with advanced lung cancer that has spread and carries a specific genetic change called a RET fusion. The trial involved 223 participants worldwide who had not yet received treatmen…

This early-stage study tested whether a special type of MRI scan, which uses inhaled xenon gas to map how well the lungs are working, could help doctors plan radiation therapy for lung cancer. The goal was to see if this detailed map could help direct radiation doses away from th…

This study tested an experimental drug called MORAb-202 in people with a specific type of advanced lung cancer that had spread and stopped responding to prior treatments. The goal was to see if the drug was safe and if it could shrink tumors. The trial was small and ended early.

This study tested whether adding an experimental drug called bemcentinib to standard chemotherapy and immunotherapy is safe and effective for people with advanced non-small cell lung cancer. It focused on patients who had not received prior treatment and included a group with a s…

This study tested a personalized treatment plan for patients with multiple early-stage lung tumors. Doctors used genetic sequencing of the tumors to guide a combination of targeted drug therapy and surgery or radiation. The goal was to see if this aggressive, tailored approach co…

This study aimed to see if a new drug called BAT3306 works similarly to the established drug Keytruda, when both are given with standard chemotherapy. It was for adults with advanced, non-squamous non-small cell lung cancer who had not received prior treatment. The main goal was …

This early-stage study aimed to test the safety and find the right dose of a new drug called Felmetatug Vedotin for people with advanced solid tumors. It was for adults with cancers like ovarian, breast, lung, and others that had spread or could not be removed by surgery. The tri…

This early, terminated study aimed to understand how two experimental cancer drugs travel to and collect in tumors. It involved 8 patients with advanced lung or head/neck cancers. Researchers used a special radioactive tracer and PET scans to take pictures showing where the drugs…