Pfizer's new cancer pill tested in advanced tumors – study halted early
NCT ID NCT06704724
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-stage study tested a new cancer pill (PF-07985045) alone or with other drugs in people with advanced solid tumors that have a KRAS gene mutation. The trial included patients with lung, colon, or pancreatic cancer. The study aimed to check safety and find the right dose, but it was terminated early. Participants took the pill in 21- or 28-day cycles and could continue until their cancer stopped responding.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Brigham and Women's Hospital
Boston, Massachusetts, 02115, United States
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City of Hope (City of Hope National Medical Center, City Of Hope Medical Center)
Duarte, California, 91010, United States
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Columbia University Irving Medical Center
New York, New York, 10032, United States
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DFCI Chestnut Hill
Newton, Massachusetts, 02467, United States
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Highlands Oncology Group
Fayetteville, Arkansas, 72703, United States
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Highlands Oncology Group
Rogers, Arkansas, 72758, United States
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Highlands Oncology Group
Springdale, Arkansas, 72762, United States
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Pan American Center for Oncology Trials, LLC
Rio Piedras, 00935, Puerto Rico
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The Trustees of Columbia University and The New York and Presbyterian Hospital
New York, New York, 10032, United States
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The University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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University of Wisconsin Carbone Cancer Center - Eastpark Medical Center
Madison, Wisconsin, 53718, United States
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University of Wisconsin Carbone Cancer Center-University Hospital
Madison, Wisconsin, 53792, United States