Tiny study uses PET scans to track cancer drug in tumors
NCT ID NCT03780725
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This early-phase study aimed to use PET imaging to track how a new drug (BI 754111) spreads in the body and reaches tumors in people with advanced non-small cell lung cancer or head and neck cancer. Only 8 participants were planned, and the study was terminated early. The main goal was to measure drug uptake in tumors using a radioactive tracer, not to test treatment effectiveness.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- BI 754111 (a drug) combined with ezabenlimab (BI 754091), plus a radioactive tracer for imaging
- What this could lead to
- If successful, this imaging method could help doctors see where the drug goes in the body and whether it reaches tumors, potentially guiding future treatment strategies.
- What could go wrong
- This was a very small, early-phase study (only 8 participants planned) that was terminated early, so results are limited and may not apply to broader patient groups.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Amsterdam UMC Locatie VUMC
Amsterdam, 1081HV, Netherlands
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