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New cancer drug QEQ278 tested in Early-Stage trial

NCT ID NCT05462873

Terminated Disease control Sponsor: Novartis Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-stage trial tested a new drug, QEQ278, in 30 adults with advanced solid tumors that had stopped responding to standard treatments. The main goals were to check the drug's safety and find the right dose. The study was stopped early, so results are limited.

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Conditions

The condition(s) this trial relates to.

esophageal squamous cell carcinoma head and neck squamous cell carcinoma human papillomavirus-related squamous cell carcinoma non-small cell lung carcinoma renal cell adenocarcinoma renal cell carcinoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARCINOMA, NON-SMALL-CELL LUNG CARCINOMA, RENAL CELL ESOPHAGEAL SQUAMOUS CELL CARCINOMA SQUAMOUS CELL CARCINOMA OF HEAD AND NECK

Contacts and locations

Locations

  • Florida Cancer Specialists

    Fort Myers, Florida, 33901, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Massachusetts General Hospital Dept. of Mass General Hospital

    Boston, Massachusetts, 02114, United States

  • Novartis Investigative Site

    Brussels, 1200, Belgium

  • Novartis Investigative Site

    Paris, 75231, France

  • Novartis Investigative Site

    Essen, 45147, Germany

  • Novartis Investigative Site

    Milan, MI, 20133, Italy

  • Novartis Investigative Site

    Kashiwa, Chiba, 2778577, Japan

  • Novartis Investigative Site

    Singapore, 168583, Singapore

  • Novartis Investigative Site

    Barcelona, 08035, Spain

  • Novartis Investigative Site

    Taipei, 10002, Taiwan

  • University of California LA

    Los Angeles, California, 90095, United States