New MRI technique aims to spare healthy lung during cancer radiation
NCT ID NCT05302817
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase trial tested whether a special MRI scan using hyperpolarized xenon gas could help doctors plan radiation therapy for non-small cell lung cancer. The goal was to map which parts of the lung are working well so radiation can avoid them, potentially reducing side effects like breathing trouble. Only 9 patients were enrolled before the study was terminated, so the findings are limited.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
hyperpolarized xenon-129 MRI
What this could lead to
If successful, this imaging technique could help doctors plan radiation therapy to avoid damaging healthy lung tissue, potentially reducing breathing problems and improving quality of life after treatment.
What could go wrong
This was a very small, early-phase trial that was terminated early, so results are limited. The approach may not work for all patients, and inhaling hyperpolarized xenon carries unknown risks in people with severely damaged lungs.
Disclaimer
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the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital of the University of Pennsylvania
Philadelphia, Pennsylvania, 19104, United States