BLEEDING

This study tested whether tranexamic acid (TXA), a drug that helps blood clot, can reduce blood loss during breast cosmetic surgery. Sixty women having breast surgery took part. Researchers measured blood loss and checked blood markers before and after surgery to see if TXA helpe…

This study looked at how well and how safely the Obsidio device blocks blood vessels to control bleeding from hypervascular tumors. It involved 125 patients in the U.S. who were treated with Obsidio. The main goals were to see if the device successfully blocked the target vessels…

This study tested the WATCHMAN FLX Pro device in 949 people with non-valvular atrial fibrillation who are at risk for stroke and bleeding. The device is implanted to close off a part of the heart where clots often form, aiming to reduce stroke risk without needing lifelong blood …

This study tested whether a purified clotting protein (fibrinogen concentrate) works as well as a blood product (cryoprecipitate) to stop bleeding in children aged 2 years or younger after heart surgery. 31 children were randomly assigned to receive one of the two treatments. The…

This study tested whether a drug called tranexamic acid (TXA) can reduce blood loss during tummy tuck surgery. Sixty adults having a tummy tuck were given either TXA or a placebo. The goal was to see if TXA helps control bleeding and improve recovery.

This study tested a new method to prevent blood clots in the dialysis machine without using heparin, a blood thinner that can increase bleeding risk. The approach uses a special calcium-free fluid with citrate and replaces calcium separately. The study included 97 critically ill …

This study tested two ways of using a breathing machine during heart bypass surgery to see which one leads to fewer lung problems. Over 1,500 adults having planned heart surgery took part. One group had the breathing machine turned off during bypass, while the other received very…

This study tested whether a pathogen-reduced blood product (INTERCEPT fibrinogen complex) works as well as standard cryoprecipitate to control bleeding in 208 adults undergoing heart or liver transplant surgery. The goal was to see if having this product readily available could r…

This study looked at whether using a person's genetic information to choose their blood thinner (clopidogrel or an alternative) leads to better outcomes after a heart procedure. About 283 adults with chronic coronary artery disease who had a stent placed were split into two group…

This study tested a new method to stop bleeding after a common heart procedure (transradial catheterization). The goal was to reduce the chance of artery blockage and bleeding while shortening the time pressure is needed. 451 adults took part, and the approach combined a lower do…

This study tested whether tranexamic acid, a drug that helps blood clot, can lower the chance of wound infections after gastrointestinal surgery. Over 3,300 adults at higher risk for complications took part. The goal was to see if this simple, low-cost approach could improve reco…

This study looked at 278 adults on a heart-lung machine (VA ECMO) to find out why some patients have dangerous bleeding. Researchers collected information on patients' health history, treatments, and lab results at the start of support. The goal was to identify early warning sign…

This study followed 167 adults with atrial fibrillation or flutter who had a catheter ablation procedure. Researchers measured changes in stroke and bleeding risk scores before and 3, 6, and 12 months after ablation. They also compared different ways to monitor heart rhythm after…

This study looked at whether it is safe to lower the platelet count that triggers a transfusion before placing a central venous catheter (a special IV line) in patients with blood disorders. Researchers compared a new, lower threshold (10,000 platelets per cubic millimeter) to th…

This study looked back at the records of over 9,000 people who had weight-loss (bariatric) surgery. The goal was to find what factors might increase the risk of bleeding during or within 30 days after surgery. By identifying these predictors, doctors hope to create a scoring syst…

This early-stage study tested a vaginal ring that slowly releases two medicines (dapivirine and levonorgestrel) over 90 days to prevent HIV and pregnancy. Forty healthy HIV-negative women used the ring to check how much drug gets into the body and if it causes any side effects or…