BLEEDING
Clinical trials for BLEEDING explained in plain language.
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Can a simple drug make brain surgery safer?
Disease control Recruiting nowThis study tests if a drug called tranexamic acid (TXA) can reduce blood loss during surgery to remove brain tumors. About 102 adults having a craniotomy will receive either TXA or a placebo during the operation. Researchers will compare blood loss and complications between the t…
Matched conditions: BLEEDING
Phase: PHASE3 • Sponsor: Stephen Lownie • Aim: Disease control
Last updated May 17, 2026 04:16 UTC
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Timing of blood thinner may prevent artery blockage after heart procedure
Disease control Recruiting nowThis study tests whether giving the blood thinner heparin before inserting a tube into the wrist artery can prevent blockage of that artery after a heart procedure. About 550 adults having a heart procedure through the wrist will be randomly assigned to get heparin either before …
Matched conditions: BLEEDING
Phase: NA • Sponsor: University Hospital, Strasbourg, France • Aim: Disease control
Last updated May 17, 2026 04:13 UTC
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New study aims to reduce surgical bleeding in kidney patients
Disease control Recruiting nowThis study tests whether giving two medicines, tranexamic acid and desmopressin, before surgery can reduce bleeding in patients with kidney problems. About 100 adults with chronic kidney disease or acute kidney injury who need noncardiac surgery will take part. The goal is to see…
Matched conditions: BLEEDING
Phase: PHASE3 • Sponsor: Hamilton Health Sciences Corporation • Aim: Disease control
Last updated May 14, 2026 12:06 UTC
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Chilled platelets may improve bleeding control in heart surgery
Disease control Recruiting nowThis study tests whether cold-stored platelets work as well as standard room temperature-stored platelets to control bleeding in adults having heart surgery. About 150 participants will be randomly assigned to receive one type of platelet transfusion. The goal is to see if a larg…
Matched conditions: BLEEDING
Phase: PHASE2 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated May 14, 2026 12:01 UTC
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Can blood thinners after bypass prevent strokes without causing dangerous bleeding?
Disease control Recruiting nowThis study looks at whether adding a blood thinner to standard aspirin therapy helps prevent strokes and blood clots in people who develop a new irregular heartbeat after coronary bypass surgery. About 3,200 adults who had bypass surgery and then had a short-lasting or repeated i…
Matched conditions: BLEEDING
Phase: PHASE3 • Sponsor: Icahn School of Medicine at Mount Sinai • Aim: Disease control
Last updated May 13, 2026 16:00 UTC
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New drug may stop bleeding after heart surgery better than standard care
Disease control Recruiting nowThis study compares two treatments for bleeding after heart surgery: FEIBA (a drug that helps blood clot) versus fresh frozen plasma (standard care). About 140 adults having non-emergency heart surgery will be enrolled. The goal is to see if FEIBA reduces the need for blood trans…
Matched conditions: BLEEDING
Phase: PHASE2 • Sponsor: Northwell Health • Aim: Disease control
Last updated May 13, 2026 15:59 UTC
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Heart pump patients may ditch aspirin, cut bleeding risk
Disease control Recruiting nowThis study looks at whether people with advanced heart failure who have a HeartMate3 heart pump can safely stop taking aspirin. The goal is to see if skipping aspirin reduces bleeding problems without increasing the risk of blood clots. About 128 participants who have had the pum…
Matched conditions: BLEEDING
Phase: PHASE4 • Sponsor: Columbia University • Aim: Disease control
Last updated May 04, 2026 16:18 UTC
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Iron infusions may ease bleeding in inherited disorders
Symptom relief Recruiting nowThis study looks at whether giving iron through a vein (IV) can reduce bleeding symptoms in people with inherited bleeding disorders who are also low in iron. About 40 participants will receive standard IV iron and be followed for 3 months to track changes in bleeding, fatigue, a…
Matched conditions: BLEEDING
Sponsor: Nicoletta C Machin • Aim: Symptom relief
Last updated May 13, 2026 16:02 UTC
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New study aims to predict dangerous clots and bleeding in heart patients
Knowledge-focused Recruiting nowThis study looks at over 12,000 people with coronary heart disease who take blood thinners. These drugs can cause serious clots or bleeding. Researchers will use advanced tests on blood samples and combine them with medical images and computer models to find better ways to predic…
Matched conditions: BLEEDING
Sponsor: Xueyan Zhao • Aim: Knowledge-focused
Last updated May 11, 2026 20:51 UTC
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Hip fracture surgery timing study aims to reduce delays for patients on blood thinners
Knowledge-focused Recruiting nowThis study looks at 374 older adults with hip fractures who take blood thinners. It compares having surgery within 24 hours versus waiting longer, to see if early surgery leads to more blood transfusions. The goal is to find out if operating sooner is safe and could reduce compli…
Matched conditions: BLEEDING
Sponsor: St. Antonius Hospital • Aim: Knowledge-focused
Last updated May 01, 2026 15:57 UTC