Can a simple drug make colorectal surgery safer?
NCT ID NCT06657924
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether giving tranexamic acid (TXA) before and after major colorectal surgery can reduce bleeding and the need for blood transfusions. About 394 adults having inpatient colorectal surgery will either receive TXA or not. The trial also checks if TXA raises the risk of blood clots.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
tranexamic acid (TXA)
What this could lead to
If it works, this could become a standard way to reduce bleeding and transfusions in colorectal surgery.
What could go wrong
This is a mid-stage trial with 394 participants, so results may not apply to all patients. TXA could increase the risk of dangerous blood clots.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for BLEEDING are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Cleveland Clinic Fairview Hospital
RECRUITINGCleveland, Ohio, 44111, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••