BIPOLAR DISORDER (BD)

This pilot study tests a structured program to help young adults (ages 18-35) recently diagnosed with bipolar disorder transition from hospital to community care. The program includes group education, one-on-one peer support, and guidance for community healthcare providers. The g…

This study tests whether a personalized nutrition plan can reduce heart disease risk in people with bipolar disorder. Participants will work with a dietitian in group and one-on-one sessions. The goal is to improve blood markers, weight, and overall heart health. The study is for…

This study is testing whether a 16-week ketogenic diet (low carb, high fat) is safe and helpful for teens and young adults (ages 12-21) with bipolar disorder who are also taking standard medications. Researchers will track mood, thinking skills, and metabolic health to see if the…

This study aims to see if a new medical device, which combines a blood test with a short questionnaire, can accurately identify bipolar disorder in people who are currently experiencing a major depressive episode. About 623 adults in primary care will provide a blood sample and a…

This study tests whether a three-week virtual reality brain-training program, combined with a daily supplement called sodium butyrate, can improve memory and thinking in 160 middle-aged and older adults who have had depression or bipolar disorder but are currently stable. Partici…

This study tests whether a safe, non-invasive brain stimulation device used at home can reduce depression in people with bipolar disorder. About 212 adults with bipolar depression will either receive real or sham (fake) stimulation for 10 weeks. The goal is to see if the device i…

This study aims to adapt and validate a short 6-question scale (HPS-6) for the Romanian population to help identify people at higher risk for bipolar disorder. Researchers will enroll 50 adults aged 18-50 who are native Romanian speakers and not currently at high risk for suicide…

This study aims to better understand high-level thinking problems—like motivation, self-awareness, and decision-making—in people with mental health or brain disorders such as schizophrenia, depression, bipolar disorder, Alzheimer's, and stroke. Researchers will compare 600 patien…

This study will follow 1,000 teenagers hospitalized for major depression or bipolar disorder. Researchers will collect data from blood tests, brain scans, wearable devices, and questionnaires to identify new risk factors and build models that predict how well a teen will respond …

This study explores whether a computer system that analyzes speech, facial expressions, eye movements, and brain signals can predict when a person with bipolar disorder might have a relapse. Researchers will enroll 200 stable bipolar patients and 200 healthy volunteers. The goal …

This study will collect genetic information and health records from 50,000 people with serious mental illnesses like bipolar disorder, schizophrenia, major depression, and dementia. Researchers will analyze this data to find better ways to diagnose and treat these conditions. Par…

This study looks at how well people with schizophrenia or bipolar disorder can exercise and breathe. Researchers will measure lung function, muscle strength, and walking ability in 150 adults aged 18 to 65. The goal is to find physical limitations and help design better exercise …

This study aims to see how faithfully people with bipolar disorder take their lithium medication in real life. About 50 participants will use a special pillbox that records when they remove a pill, and they will get weekly phone calls to compare their reported intake with the rec…