B-CELL LYMPHOMA

This study follows patients who previously received AvenCell's CAR-T cell therapy in earlier clinical trials. Researchers want to understand the long-term safety and effectiveness of these cancer treatments over time. The study will track 178 patients with various blood cancers a…

This study is testing the safety and effectiveness of combining two drugs, venetoclax and inotuzumab ozogamicin, for adults with B-cell acute lymphoblastic leukemia (B-ALL) that has come back or hasn't responded to previous chemotherapy. The main goal is to find the highest safe …

This early-stage study is testing the safety and initial effectiveness of a new oral drug called LOXO-338 for patients with advanced blood cancers like leukemia and lymphoma who have already received standard therapies. The trial has two parts: first testing LOXO-338 alone, and t…

This study aimed to test if the drug glofitamab could prevent cancer from returning in patients with large B-cell lymphoma. It was designed for people who had completed standard first treatment successfully but still had tiny amounts of cancer cells detectable in their blood. The…

This study is testing whether combining two oral drugs, palbociclib and ibrutinib, can help control mantle cell lymphoma in patients whose cancer has returned or worsened after at least one prior treatment. The main goal is to see how long the combination can keep the cancer from…

This early-stage trial aims to find a safe and tolerable dose of a new drug, loncastuximab tesirine, when combined with a standard chemotherapy regimen (DA-EPOCH-R). It is for adults with aggressive types of B-cell lymphoma, including Burkitt lymphoma, who have not yet received m…

This is a first-in-human safety study testing a new, experimental CAR-T cell therapy called CAR19.20.22 in adults with B-cell lymphomas that have returned or not responded to at least two prior treatments. The therapy uses the patient's own immune cells, engineered to attack canc…

This is an early-stage safety study testing a new type of treatment for patients whose B-cell lymphoma or leukemia has returned or not responded to standard therapies. Doctors take a patient's own immune cells (T cells), genetically modify them in a lab to better recognize and at…

This study is testing if a drug called anakinra can prevent or reduce severe brain-related side effects and dangerous immune reactions in adults receiving CAR-T cell therapy for certain B-cell cancers. The goal is to make this powerful cancer treatment safer by controlling its mo…

This study is testing a new blood test, called a 'liquid biopsy,' to see if it can better predict whether lymphoma will come back after initial treatment. It will compare the blood test results to the standard PET-CT scan in 108 patients with B-cell or Hodgkin lymphoma. The goal …