CAR-T therapy patients monitored for years in new safety study

NCT ID NCT07474051

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study follows 178 patients who previously received an AvenCell CAR-T cell therapy for cancers like lymphoma, leukemia, or prostate cancer. Researchers will track delayed side effects, including new cancers or autoimmune issues, for years. No new treatment is given—this is purely a long-term safety check.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

CAR-T cell therapy (UniCAR or RevCAR platforms)

What this could lead to

If successful, this study could provide crucial safety data to support the broader use of these CAR-T therapies.

What could go wrong

This is a long-term follow-up study, not a treatment trial. It cannot prove the therapy works, and results depend on patient participation and data quality.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute myeloid leukemia B-cell chronic lymphocytic leukemia B-cell neoplasm hematopoietic and lymphoid cell neoplasm hematopoietic and lymphoid system neoplasm prostate cancer

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Charité Universitätsmedizin Berlin

    Berlin, Germany

  • Klinikum der Universität (LMU) Muenchen

    Munich, Germany

  • Technische Universitaet Dresden - Universitaetsklinikum Carl Gustav Carus

    Dresden, Germany

  • Universitatsklinikum Ulm

    Ulm, Germany

  • Universitätsklinikum Marburg

    Marburg, Germany