New combo therapy shows promise for hard-to-treat leukemia

NCT ID NCT05016947

First seen Jan 31, 2026 · Last updated May 12, 2026 · Updated 16 times

Summary

This early-phase study tests whether combining two drugs, venetoclax and inotuzumab ozogamicin, is safe and effective for people with B-cell acute lymphoblastic leukemia (B-ALL). About 23 adults with CD22-positive B-ALL that has come back or not responded to treatment will receive the combination. The goal is to find the best dose and see how many achieve complete remission.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States

Conditions

Explore the condition pages connected to this study.