New drug combo shows promise in early trial for tough blood cancer

NCT ID NCT05016947

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This early-phase study tests whether combining two drugs, venetoclax and inotuzumab ozogamicin, is safe and effective for people with B-cell acute lymphoblastic leukemia (B-ALL), a fast-growing blood cancer. About 23 adults whose cancer has returned or not responded to treatment will receive the combination. The goal is to find the best dose and see if it can lead to remission.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary โ€” we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia B-cell acute lymphoblastic leukemia B-cell neoplasm B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2) blast phase chronic myelogenous leukemia, BCR-ABL1 positive Burkitt lymphoma lymphoblastic lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02115, United States