AUTISM

This study tests a program that gives pregnant women personalized nutrition and lifestyle advice based on their genes and nutrient levels. The goal is to see if this approach can lower the chances of problems like preterm birth, preeclampsia, and gestational diabetes. About 500 p…

This study tests whether a full-spectrum cannabis plant extract called NTI164 can help reduce core autism symptoms like social difficulties and repetitive behaviors. About 98 children and young adults aged 6 to 25 with moderate to severe autism will receive either NTI164 or a pla…

This study tests whether inhaling a gas called xenon for 10 minutes each day can improve social skills in children with autism. 72 children aged 4-18 will receive either xenon or a placebo gas for 10 days. Researchers will check for changes in social behavior and safety right aft…

This study tests a non-invasive brain stimulation technique called rTMS in 80 children and teens (ages 6-19) with ADHD or autism. Participants will receive either real or sham (fake) stimulation over 3 weeks to see if it safely reduces core symptoms. The goal is to explore a pote…

This study tests a culturally adapted version of the RUBI parent training program for Spanish-speaking families of autistic children aged 2 to 9. About 120 parents will join online group sessions and use a Spanish handbook to learn practical strategies for managing challenging be…

This study will test if a special light treatment, called photobiomodulation, can help reduce core autism symptoms like trouble with socializing and communication. Thirty children with autism, ages 2 to 6, will receive the light therapy along with standard physical, occupational,…

This study tests a program called MENU for families of young children (ages 2-5) who are waiting for an autism evaluation. The program gives caregivers tools to improve their own mental health and help with their child's communication and behavior. About 60 underserved families i…

This study tests an investigational drug called Omega-DEK plus L-carnitine in 34 children aged 3 to 6 with childhood apraxia of speech (CAS). The 20-week trial first gives everyone the treatment for 12 weeks, then randomly assigns some to a placebo for 8 weeks to see if symptoms …

This study tests two ways to deliver a group training program for caregivers of children with autism in low-resource areas. The goal is to reduce caregiver stress and improve the child's communication and behavior. About 320 caregivers of children aged 2 to 8 years will take part…

This study tests if toe-spreading exercises, with or without walking on different surfaces, can improve foot arch and jumping ability in children with autism who have flat feet. Thirty-four children aged 7 to 12 will do the exercises three times a week for eight weeks. Researcher…

This study tests whether playing a virtual reality (VR) game twice a week for 6 weeks can improve sustained attention in neurodivergent children aged 9 to 18. Participants include children with autism, ADHD, learning differences, or coordination challenges. The study uses eye-tra…

This study compares two well-known early autism treatments, ESDM and PRT, to see which one helps young children with autism improve their communication skills the most. About 140 children aged 2 to 4 years 11 months will be randomly assigned to one of the two therapies for 24 wee…

This study tests a short, guided self-help program designed to help parents of autistic children (ages 6-17) manage stress and improve well-being. Parents will read workbook materials, listen to audio tracks, and have weekly support calls with a researcher over about 13 weeks. Th…

This early-stage trial tests whether a 6-week course of vancomycin followed by a fecal transplant from a family member can improve social and language delays in adults with autism. Ten participants with gastrointestinal symptoms will be monitored for changes in autism symptoms an…

This study tests whether the anti-inflammatory drug prednisone can improve core autism symptoms in adult males with a specific immune-related form of autism. Over 16 weeks, 32 participants will receive either prednisone or a placebo, with regular checkups and remote calls. The go…

This study looks at stored urine and blood samples from 600 first-time mothers to find early signs that might predict autism in their children. Researchers will check for pesticides and other chemicals in the mother's urine, and study certain substances in the blood. The goal is …

This study tests a brief online program called Project Independence for caregivers of autistic youth ages 10 to 14. The program gives caregivers practical tools to help their child become more independent in daily tasks like getting dressed or doing chores. About 70 caregivers wi…

This study tests a mobile health program called FANS-EI that aims to help caregivers of young autistic children stay engaged in early interventions. Researchers will measure caregiver comfort, participation, and feelings of support. The study involves 28 caregiver-child pairs and…

This study will test a special language teaching method for infants aged 6-12 months who have an older sibling with autism. These infants are at higher risk for autism or language delays. The method encourages babies to look at their caregiver's mouth during play, which may help …

This pilot study aims to improve mental health treatment for autistic individuals. Researchers will first hold focus groups to understand barriers to care, then develop a resource for therapists. The toolkit will be tested in a community clinic with 18 autistic teens aged 13-17 w…

This study explores how to better include autistic people in conversations about behavioral interventions like Applied Behavior Analysis (ABA). Researchers will bring together autistic individuals, ABA providers, and others to test different engagement methods. The goal is to cre…

This study tests a new training program called CIPP-A for pediatric providers who care for autistic youth. The goal is to see if the program is easy to use and helps providers feel more confident in managing suicide risk. About 70 providers will be randomly assigned to receive ei…

This study tests a new computer program designed to help autistic children ages 8-11 improve their ability to control thoughts and actions, which may reduce repetitive behaviors. About 95 children will be randomly assigned to receive the training right away or after a delay. Rese…

This study looks at whether a parent training program can help autistic toddlers (12-36 months) manage their emotions better. Researchers will work with 40 families and early intervention providers to see if the program is practical and helpful. The goal is to improve support for…

This study looks at whether how children with autism process sensory information is connected to tightness in their ankle muscles. Researchers will observe toe-walking, measure ankle flexibility, and have parents fill out a sensory questionnaire. The goal is to better understand …