AUTISM

This study tests a telehealth program that teaches parents of children with autism and overweight or obesity how to help their child manage weight through nutrition, activity, and behavior skills. About 140 families will take part, with one group receiving the parent-based progra…

This study tests whether a mix of treatments—including the patient's own stem cells, a strict keto diet, and a fecal transplant—can improve social skills, communication, and gut health in 50 teens and adults with autism. Participants must be stable on their current medications. T…

This study tests a drug called CM-AT in children with autism who have low levels of a digestive enzyme. The goal is to see if the drug is safe and helps with behaviors like irritability and social withdrawal over a longer period. About 405 children aged 3 to 8 who completed a pre…

This study tests whether DHA, a key omega-3 fatty acid found in fish oil, can improve symptoms of autism in children and adolescents aged 5 to 17. Participants receive either DHA or a placebo daily for 12 weeks. Researchers also look at genes and urine markers related to DHA to u…

This study tests an internet-based cognitive behavioral therapy (CBT) program designed to help autistic adolescents aged 11-17 manage anxiety. The program, called LUNA-Adolescent, is parent-led and delivered online, making it easier for families who cannot access in-person therap…

This study tests whether a parent-led therapy called Pathways can improve social skills in 80 toddlers (16-30 months old) who show early signs of autism. One group of parents learns a technique to encourage mutual eye contact during play, while the other group uses the same thera…

This study tests whether a probiotic supplement called Neuralli® MP can help adults aged 18 to 50 who have autistic traits. Participants take two capsules daily and set their own personal goals to track progress. The trial is small and open-label, meaning everyone knows they are …

This small pilot study at Yale University is testing a modified form of cognitive-behavioral therapy (CBT) for children with autism and intellectual disability who struggle with irritability, tantrums, and aggression. Up to 6 children aged with an IQ between 55 and 85 will receiv…

This study tests whether children with autism will do daily 5-10 minute exercises if they see themselves, other kids, or kids in rabbit suits in a mobile app. Twenty children and their parents will use the app for 8 weeks. Researchers will measure how long kids stick with the exe…

This study tests whether ChatGPT can act as a job coach for adults with autism spectrum disorder (ASD). Thirty motivated adults aged 18-45 will use ChatGPT to build resumes, practice interviews, and discuss workplace social skills over one week. Researchers will measure changes i…

This study tests whether a type of brain stimulation called rTMS can reduce depression in people with autism. Twenty-four participants aged 13 to 26 will receive either real or sham (fake) stimulation to see if it helps. The goal is to find a new way to treat depression that hasn…

This study tests a 14-day digital writing program designed to help parents of autistic individuals manage stress and improve mental health. Participants use a WeChat mini-program to write about their feelings and practice self-kindness for about 5 minutes each day. The trial incl…

This phase 2 trial tests whether sulforaphane, a compound found in broccoli, can improve core symptoms of autism. 48 males aged 13-30 with autism will receive either sulforaphane or a placebo for several weeks. Researchers will measure changes in behavior and social responsivenes…

This study tests whether cannabidiol (CBD) can reduce severe behavior problems like aggression, self-harm, and repetitive actions in children with autism. About 42 boys aged 7-14 with severe autism and daily behavioral issues will receive both CBD and a placebo at different times…

This study tests a brain training method that combines EEG and fNIRS to help autistic children aged 8 to 12 improve attention, emotion control, and social skills. Thirty children will receive neurofeedback sessions and complete thinking and behavior assessments. The goal is to se…

This study aims to uncover the genetic and environmental factors behind autism spectrum disorders (ASD), including autism, Asperger's syndrome, and PDD. Researchers will analyze gene expression in 240 participants aged 18 months and older who have an ASD diagnosis. The goal is to…

This observational study follows 36 people with neurologic conditions like traumatic brain injury, cerebral palsy, multiple sclerosis, or Alzheimer's who are already receiving intranasal MuSE stem cell or exosome therapy as part of their routine care. Researchers track safety and…

This study planned to use high-frequency brain signals to locate important brain areas and understand conditions like epilepsy, migraine, and ADHD. It aimed to create a large database of brain activity in people aged 1 day to 69 years. However, the study was withdrawn before any …

Researchers at Arkansas Children's Hospital are studying how mitochondria work in children with autism spectrum disorder. They aim to identify distinct patterns of mitochondrial dysfunction that may relate to developmental delays. The study involves up to 5 visits with blood draw…

This study uses brain scans and magnetic stimulation to compare brain activity in 160 adults with autism, depression, both, or neither. Researchers want to understand how brain inflammation and the balance of excitation and inhibition relate to social and emotional symptoms. No t…

This study looks at whether a parent coaching and family navigation program (Project AFECT) can help families right after a child is diagnosed with autism. About 200 parents of children aged 1 to 5, who are Hispanic/Latino, Black/African-American, or have Medi-Cal insurance, will…

This small pilot study aims to see if digital biomarkers—like heart rate and movement tracked by a watch—can help measure changes in autism symptoms during treatment with sulforaphane, a compound found in vegetables. Ten males aged 13-30 with autism who previously took part in a …

This study looks at spinal posture, balance, and ankle muscle tightness in children with autism compared to typically developing children. Researchers will measure these physical traits using tools like the Spinal Mouse and balance tests. The goal is to understand if children wit…