Could a poop transplant ease autism? small trial aims to find out

NCT ID NCT04630847

Not yet recruiting Symptom relief Sponsor: ProgenaBiome Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This early-phase trial tests whether giving adults with autism a 6-week course of vancomycin followed by a fecal transplant from a close relative can improve social and language problems. Ten participants will be tracked for changes in autism symptoms, quality of life, and gut health. The goal is to see if adjusting gut bacteria can ease core autism challenges.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: vancomycin followed by fecal microbiota transplant from a first-degree relative
What this could lead to: If it works, this could point toward a way to improve social skills and language in some adults with autism by changing their gut bacteria.
What could go wrong: This is a very early, small trial with only 10 people, so results may not apply to everyone. The procedure also carries risks like infection or digestive upset.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

autism autism spectrum disorder Dysbiosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

AUTISM AUTISM SPECTRUM DISORDER

Contacts and locations

Locations

ProgenaBiome

Ventura, California, 93003, United States

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