AORTIC VALVE DISEASE

This study is testing a device that replaces both a faulty heart valve and a damaged section of the main artery (aorta) in one surgery. About 260 people worldwide will receive the Abbott Valved Graft. Researchers will track how many patients survive and whether they need another …

This study tests a new, less invasive heart valve implant for people with severe aortic regurgitation (a leaky heart valve). About 210 participants will be randomly assigned to get the new valve or standard care. The main goal is to see if the implant reduces the risk of death, s…

This study follows 225 adults with aortic valve disease who undergo the Ross procedure, a surgery that replaces the diseased valve with the patient's own pulmonary valve. Researchers will track survival, hospital readmissions, and need for repeat surgeries over 1, 5, and 10 years…

This study tests a new heart valve (JenaValve Trilogy) placed without open-heart surgery in 50 adults who have a left ventricular assist device (LVAD) and a leaky aortic valve. The goal is to see if the valve is safe and works well to improve blood flow and reduce complications. …

This study explores whether a portable device that measures chest vibrations (kinocardiography) can help diagnose aortic valve disease and thoracic aortic aneurysm. Researchers will compare these signals with standard imaging in 180 adults, including healthy controls. The goal is…

This study follows 10,000 adults with heart valve disease to understand how the condition progresses and what factors influence it. Researchers will use imaging tests like echocardiograms, CT scans, and MRIs, along with medical history and lifestyle information. The goal is to pr…

This study watches which guidewires doctors use during a TAVI procedure—a minimally invasive way to replace a heart valve. Researchers want to see if a newer wire, the Savvywire, offers extra benefits over standard wires. About 300 people aged 50 or older getting a TAVI through t…

This study is a registry that gathers information from 500 people who need a new aortic valve. It looks at how well the INSPIRIS RESILIA valve works over time by measuring blood flow and any leaks. The goal is to see how the valve performs in everyday medical practice, not just i…

This study looks at 80 people who develop a new heart block after TAVI (a procedure to replace a heart valve). Participants get a small heart monitor implanted under the skin to watch for dangerous heart rhythm problems over time. The goal is to learn how often these problems hap…