AORTIC VALVE DISEASE
Clinical trials for AORTIC VALVE DISEASE explained in plain language.
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Living valve replacement study aims to reduce lifetime medication need
Disease control Recruiting nowThis study follows patients who undergo the Ross procedure, a special type of heart valve surgery. The procedure replaces a damaged aortic valve with the patient's own living pulmonary valve, avoiding the need for lifelong blood thinners required with mechanical valves. Researche…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Baylor Research Institute • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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New hope for heart pump patients with failing valves
Disease control Recruiting nowThis study is testing a new, less invasive heart valve replacement procedure for patients who have mechanical heart pumps (LVADs) and develop leaky aortic valves. The procedure uses a device called the JenaValve Trilogy system, which is inserted through blood vessels without open…
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: JenaValve Technology, Inc. • Aim: Disease control
Last updated Mar 24, 2026 12:02 UTC
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Heart valve procedure wires under the microscope
Knowledge-focused Recruiting nowThis study aims to observe and compare different guidewires used during TAVI procedures, a minimally invasive heart valve replacement. Researchers will collect data from 300 patients aged 50 and older who are undergoing the standard TAVI procedure. The goal is to see if a newer w…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: dr Pim A.L. Tonino • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:33 UTC
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Tiny heart monitor tracks hidden dangers after valve surgery
Knowledge-focused Recruiting nowThis study aims to understand how often patients develop dangerous heart block after a minimally invasive aortic valve replacement (TAVI) if they also develop a new, persistent electrical problem called left bundle branch block (LBBB). Researchers will implant a small, matchbox-s…
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: Centre de Recherche de l'Institut Universitaire de Cardiologie et de Pneumologie de Quebec • Aim: Knowledge-focused
Last updated Mar 30, 2026 14:30 UTC
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Massive 10,000-Person study aims to predict heart valve failure
Knowledge-focused Recruiting nowThis study aims to understand how moderate heart valve disease gets worse over time. It will follow 10,000 adults in China, using regular heart scans and blood tests to track their condition. The goal is to find early warning signs and see how different treatments affect the dise…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:41 UTC
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Doctors track 500 patients to see how new heart valve performs
Knowledge-focused Recruiting nowThis study aims to collect real-world information on how well a specific artificial aortic heart valve works over time. It will follow 500 patients in Germany who receive this valve as part of their standard medical care. The main goal is to monitor the valve's performance, inclu…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Edwards Lifesciences • Aim: Knowledge-focused
Last updated Mar 27, 2026 12:40 UTC