AORTIC VALVE DISEASE
Clinical trials for AORTIC VALVE DISEASE explained in plain language.
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New tiny heart valve offers hope for kids with aortic disease
Disease control OngoingThis study looks at a small mechanical heart valve (15mm) designed for children who need their aortic valve replaced. About 20 kids will get the valve and be followed for 5 years to check for serious side effects like blood clots, bleeding, or valve failure. The goal is to see if…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 17, 2026 10:46 UTC
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New heart valve study aims to improve safety and blood flow
Disease control OngoingThis study looks at how safe and effective the Avalus Ultra heart valve is for people with aortic valve disease. About 190 participants will receive the valve and be followed for one year. Researchers will track complications, blood flow through the valve, and changes in heart fa…
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: Medtronic Cardiac Surgery • Aim: Disease control
Last updated May 17, 2026 10:40 UTC
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New heart valve trial offers hope without Open-Heart surgery
Disease control ENROLLING_BY_INVITATIONThis study tests a new heart valve device (Navitor TAVI) for people with severe aortic stenosis, a condition where the heart's main valve becomes narrow. It includes 1,500 participants who are at low or intermediate risk for surgery. The goal is to see if the device is safe and e…
Matched conditions: AORTIC VALVE DISEASE
Phase: NA • Sponsor: Abbott Medical Devices • Aim: Disease control
Last updated May 17, 2026 10:26 UTC
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Common arthritis drug could be first pill for deadly heart valve disease
Disease control OngoingThis study tests whether colchicine, an anti-inflammatory drug, can slow the progression of aortic valve stenosis—a common heart valve disease that currently has no medication. About 150 adults with moderate, symptom-free valve narrowing will take colchicine and be monitored with…
Matched conditions: AORTIC VALVE DISEASE
Phase: PHASE3 • Sponsor: Radboud University Medical Center • Aim: Disease control
Last updated May 14, 2026 12:02 UTC
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Heart valve patients may go home in 24 hours: major safety trial underway
Symptom relief OngoingThis study looks at whether it is safe for people with narrowed heart valves to be discharged just 24 hours after a minimally invasive valve replacement (TAVI). Researchers will track 585 patients for complications like stroke, heart attack, or need for a pacemaker. The goal is t…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Fundación EPIC • Aim: Symptom relief
Last updated May 17, 2026 10:27 UTC
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Real-World study tracks aortic valve replacement outcomes
Knowledge-focused OngoingThis study followed 900 adults who had aortic valve replacement to see how safe and effective the procedure is in everyday hospital settings. Researchers tracked deaths from any cause and heart-related deaths. The goal is to understand real-world results beyond controlled clinica…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Seung-Jung Park • Aim: Knowledge-focused
Last updated May 17, 2026 10:28 UTC
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Scientists hunt for hidden genes behind deadly aortic aneurysms
Knowledge-focused OngoingThis study aims to find the genes that cause or worsen aortic aneurysms and heart valve problems. Researchers will collect blood and tissue samples from 3000 people with these conditions, plus their family members. The goal is to build a biobank for future research, not to test a…
Matched conditions: AORTIC VALVE DISEASE
Sponsor: Yale University • Aim: Knowledge-focused
Last updated May 13, 2026 15:59 UTC