New device aims to catch debris during heart procedure, reduce stroke risk

NCT ID NCT07276711

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests a new device called EmStop that captures debris during a heart valve replacement procedure (TAVR) for aortic stenosis. About 663 people will be randomly assigned to receive either the EmStop device or a standard device. The goal is to see if EmStop reduces the risk of major heart and brain events, like stroke, within 30 days after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

EmStop Embolic Protection System (device)

What this could lead to

If successful, this device could make TAVR safer by reducing the risk of stroke and kidney damage from debris.

What could go wrong

This is an early-stage trial with 663 participants, and the device may not significantly reduce complications compared to existing options.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Aortic Valve Disease aortic valve disorder aortic valve stenosis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Mission Health

    RECRUITING

    Asheville, North Carolina, 28801, United States

    Contact

  • Monument Health Heart and Vascular Institute

    RECRUITING

    Rapid City, South Dakota, 57701, United States

    Contact

  • Ochsner Medical Center

    RECRUITING

    New Orleans, Louisiana, 70121, United States

    Contact