ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Clinical trials for ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS) explained in plain language.
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Tailored breathing support may reduce lung injury in ECMO patients
Disease control Not yet recruitingThis study tests whether personalized ventilator settings can reduce lung injury in adults with severe respiratory failure who are on ECMO (a heart-lung machine). Researchers will use esophageal manometry or electrical impedance tomography to tailor the ventilator's positive pres…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: University of California, San Diego • Aim: Disease control
Last updated Aug 08, 2026 00:03 UTC
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Could a common steroid save lives in severe lung failure?
Disease control Not yet recruitingThis study tests whether the steroid dexamethasone, when added to standard care, can lower the chance of death within 90 days for people with a serious lung condition called ARDS caused by sepsis. About 1,474 adults on breathing machines will take part. The goal is to see if this…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE3 • Sponsor: Southeast University, China • Aim: Disease control
Last updated Jul 02, 2026 00:00 UTC
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Ancient herbal remedy takes on deadly lung condition in major trial
Disease control Not yet recruitingThis study tests whether a traditional Chinese herbal formula, Xuanbai Shengmai Decoction, can improve survival in adults with acute respiratory distress syndrome (ARDS), a severe lung condition often seen in the ICU. About 308 participants will receive either the herbal decoctio…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE3 • Sponsor: Southeast University, China • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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New lung-saving strategy aims to cut deadly ARDS complications
Disease control Not yet recruitingThis study tests a new way to use breathing machines for people with severe lung failure (ARDS). The goal is to reduce lung damage by using very gentle breaths and adding a machine that helps remove carbon dioxide from the blood. About 290 adults on breathing machines for less th…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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Could a shock drug help ARDS patients breathe easier?
Disease control Not yet recruitingThis study tests an experimental drug called centhaquine in 80 adults with moderate to severe ARDS, a life-threatening lung condition. The drug is added to standard care to see if it improves oxygen levels and reduces deaths. Participants must be in the ICU and start treatment wi…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: PHASE2 • Sponsor: Pharmazz, Inc. • Aim: Disease control
Last updated Jun 27, 2026 12:07 UTC
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New position therapy could save ARDS patients from deadly complications
Disease control Not yet recruitingThis study looks at whether lying on the side at different angles can improve lung function in people with acute respiratory distress syndrome (ARDS), a serious lung condition. About 140 adult patients will be randomly placed in either the standard face-down position or a side-ly…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: The Fourth Affiliated Hospital of Zhejiang University School of Medicine • Aim: Disease control
Last updated Jun 27, 2026 09:00 UTC
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Ventilator may harm the brain, not just the lungs – study eyes link
Knowledge-focused Not yet recruitingThis study looks at whether the force of mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) can damage the brain. Researchers will measure a protein called S100B in the blood, which is a sign of brain injury, and track thinking and memory problems …
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jul 29, 2026 00:00 UTC
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New study aims to Fine-Tune ventilator strategies for ARDS patients
Knowledge-focused Not yet recruitingThis study looks at two bedside methods to measure how much of the lung can be reopened in patients with acute respiratory distress syndrome (ARDS) who are on a ventilator. It also compares four different ways to set the ventilator's positive end-expiratory pressure (PEEP). The g…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Oriol Roca • Aim: Knowledge-focused
Last updated Jul 22, 2026 00:00 UTC
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ARDS ventilator tool faces reliability test
Knowledge-focused Not yet recruitingThis study looks at whether the recruitment-to-inflation ratio (R/I ratio), a measurement used to guide ventilator settings in patients with acute respiratory distress syndrome (ARDS), gives the same result when repeated in the same patient. Researchers will measure it twice in 8…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:03 UTC
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New ICU strategy aims to close deadly gap for hispanic patients with respiratory failure
Knowledge-focused Not yet recruitingHispanic patients are twice as likely to die from respiratory failure as non-Hispanic patients, partly due to deeper sedation and less physical therapy. This pilot study will test a 'safer sedation bundle'—a set of tools and practices to help ICU staff follow guidelines more clos…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: New York University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:32 UTC
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ER study to determine best breathing aid for oxygen crisis
Knowledge-focused Not yet recruitingThis study will compare two non-invasive breathing support methods—a face mask that pushes air in and a special nasal tube that delivers high-flow oxygen—for adults in the emergency room with dangerously low blood oxygen. About 500 participants will be randomly assigned to one me…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Ohio State University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:31 UTC
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Can adjusting ventilators protect kidneys in lung failure?
Knowledge-focused Not yet recruitingThis study will observe 40 adults with acute respiratory distress syndrome (ARDS) on ventilators. Researchers will adjust the ventilator's pressure settings and use ultrasound to measure vein congestion, checking if certain settings are linked to better kidney outcomes. The goal …
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Fayoum University • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Pilot study to test best ventilator approach for severe lung failure
Knowledge-focused Not yet recruitingThis pilot study will enroll 80 ICU patients with acute hypoxemic respiratory failure to compare two ventilator strategies: one that allows patients to breathe spontaneously and one that fully controls their breathing. The goal is to see if a larger trial is possible and to gathe…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Phase: NA • Sponsor: Oslo University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:00 UTC
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New study to reveal hidden impact of ventilator settings on veins
Knowledge-focused Not yet recruitingThis study looks at how different levels of breathing support (PEEP) affect blood flow congestion in the veins of patients with acute respiratory distress syndrome (ARDS). Researchers will use ultrasound to grade congestion in the liver, kidney, and portal veins as absent, modera…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: University Hospital, Angers • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:11 UTC
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Scientists hunt for biomarkers to personalize ventilator care in ARDS
Knowledge-focused Not yet recruitingThis observational study will analyze blood and sputum samples from 411 adults with acute respiratory distress syndrome (ARDS) who are on ventilators. Researchers will look for patterns in microbes, metabolites, and gene activity to see if they can predict how well patients respo…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Ruijin Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:01 UTC
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800 ARDS patients to be studied for better treatment insights
Knowledge-focused Not yet recruitingThis study will follow 800 adults with acute respiratory distress syndrome (ARDS) in a Korean hospital to learn about their symptoms, treatments, and outcomes. Researchers will collect data from medical records and monitor how different ventilator settings affect recovery. The go…
Matched conditions: ACUTE RESPIRATORY DISTRESS SYNDROME (ARDS)
Sponsor: Jee Hwan Ahn • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC