Ventilator may harm the brain, not just the lungs – study eyes link
NCT ID NCT07629973
First seen Jun 24, 2026 · Last updated Jul 28, 2026 · Updated 4 times
Summary
This study looks at whether the force of mechanical ventilation in patients with acute respiratory distress syndrome (ARDS) can damage the brain. Researchers will measure a protein called S100B in the blood, which is a sign of brain injury, and track thinking and memory problems over a year. The goal is to understand if certain ventilator settings raise the risk of long-term cognitive issues. 150 adults with ARDS will be enrolled.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this study could help identify which ARDS patients are at highest risk for long-term brain damage, leading to better protective ventilation strategies.
- What could go wrong
- This is an observational study, not a treatment trial. It will not test any new therapy, and the link between ventilation and brain injury remains unproven in humans.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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