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Vertebral column disorder
MONDO:0000812A disease involving the vertebral column.
Also known as: disease of spine, disease of vertebral column, disease or disorder of vertebral column, disorder of vertebral column, vertebral column disease, vertebral column disease or disorder, spinal disease
1243 clinical trials for this condition and its sub-types, 82 tagged with Vertebral column disorder itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Vertebral column disorder
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Spinal cord injury 650 trials
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Intervertebral disk degenerative disorder 123 trials · 217 incl. sub-types
3 sub-types
- Lumbar disk degenerative disorder 165 trials
- Cervical disk degenerative disorder 42 trials
- Thoracic disk degenerative disorder 2 trials
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Spinal stenosis 120 trials · 154 incl. sub-types
1 sub-type
- Lumbar spinal stenosis 99 trials
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Vertebral disorder 3 trials · 130 incl. sub-types
3 sub-types
- Spondylitis 8 trials · 120 incl. sub-types Sub-types →
- Spondylolysis 6 trials
- Kummell disease 1 trial
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Vertebral joint disorder 0 trials · 118 incl. sub-types
2 sub-types
- Ankylosing spondylitis 110 trials · 114 incl. sub-types Sub-types →
- Infectious discitis 4 trials Sub-types →
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Lumbar disk disease 82 trials
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Coccygodynia 19 trials
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Spondylocostal dysostosis 5 trials · 8 incl. sub-types
4 sub-types
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Epidural spinal canal neoplasm 3 trials · 5 incl. sub-types
2 sub-types
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Sacrum chordoma 4 trials
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Sacrococcygeal teratoma 2 trials
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Baastrup syndrome 0 trials
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Dropped head syndrome 0 trials
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Lumbosacral lipoma 0 trials
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Tuberculosis, spinal 0 trials
Most studied deeper sub-types
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New bone graft aims to cut repeat surgeries in spine deformity patients
Disease control CompletedThis study compared a new bone graft material (ABM/P-15) to the standard bone graft in 120 adults having surgery for spinal deformity. The goal was to see if the new graft leads to fewer additional surgeries and better bone healing. Patients were randomly assigned to receive eith…
Sponsor: Rigshospitalet, Denmark • Aim: Disease control
Last updated Jun 27, 2026 13:07 UTC
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Spinal implants pass 24-Month safety check in 77 patients
Disease control CompletedThis study followed 77 adults who received spinal implants (PASS LP, PASS DEGEN, or PASS TULIP PRIME) to treat degenerative spine conditions like disc degeneration or spinal deformity. The main goal was to see if the bones fused properly after 24 months. Researchers also tracked …
Sponsor: Medicrea International • Aim: Disease control
Last updated Jun 27, 2026 12:28 UTC
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Spinal surgery bleeding: which dose of TXA works best?
Disease control CompletedThis completed study tested two doses of the drug tranexamic acid (TXA) in 62 adults undergoing multilevel spinal surgery. The goal was to see which dose better reduces blood loss and the need for blood transfusions. Results could help surgeons choose the safest and most effectiv…
Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital • Aim: Disease control
Last updated Jun 27, 2026 08:04 UTC
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Can ultrasound dye reveal spinal cord damage Mid-Surgery?
Diagnosis CompletedThis trial tests whether contrast-enhanced ultrasound can detect spinal cord injury during decompression surgery for chronic spinal cord compression. Researchers inject an ultrasound contrast agent before, during, and after the procedure to visualize blood flow changes in the spi…
Sponsor: Medical University of South Carolina • Aim: Diagnosis
Last updated Sep 06, 2026 00:00 UTC
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No-Radiation scoliosis screening could spare thousands of girls from unnecessary x-rays
Diagnosis CompletedThis study tested whether a radiation-free ultrasound system can accurately screen for scoliosis in 442 Hong Kong schoolgirls aged around 10, who are at high risk for curve progression. The goal was to see if ultrasound could identify which girls truly need an X-ray, reducing unn…
Sponsor: Chinese University of Hong Kong • Aim: Diagnosis
Last updated Jun 27, 2026 12:01 UTC
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Can numbing cream boost recovery after spinal injury?
Symptom relief CompletedThis early study tests a simple idea: temporarily numbing non-paralyzed arm muscles with an over-the-counter lidocaine cream while exercising paralyzed muscles. Researchers hope this will improve strength, function, and sensation in people with spinal cord injury. About 30 adults…
Phase 1 • Sponsor: University of Texas Rio Grande Valley • Aim: Symptom relief
Last updated Aug 02, 2026 00:00 UTC
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Spine surgery pain relief: which additive works best?
Symptom relief CompletedThis study tested whether adding dexamethasone or dexmedetomidine to a standard nerve block (erector spinae plane block) could extend pain relief after spine surgery. 90 adults undergoing lumbar spine surgery received one of the two additives or a placebo. The main goal was to se…
Phase 4 • Sponsor: Poznan University of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 12:32 UTC
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Simple neck lessons ease Pain-Related disability in caregivers
Symptom relief CompletedThis study tested a five-day neck education program for 62 parents of children with disabilities who had chronic neck pain. The program taught neck anatomy, proper posture, ergonomics, and exercises. After 12 weeks, parents who took the program reported less neck-related disabili…
Sponsor: Kirsehir Ahi Evran Universitesi • Aim: Symptom relief
Last updated Jun 27, 2026 12:09 UTC
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New CT-guided screw technique may spare spine patients from repeat surgery
Symptom relief CompletedThis study tested a minimally invasive procedure called CT-guided trans-facet screw fixation for 24 patients whose spine became unstable after a prior back surgery (laminectomy). Instead of open surgery under general anesthesia, the procedure uses a CT scan to guide small screws …
Sponsor: Centre Hospitalier Universitaire de Nice • Aim: Symptom relief
Last updated Jun 27, 2026 12:02 UTC
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New Mini-Invasive spine surgery aims to cut risks for scoliosis patients
Symptom relief CompletedThis study tested a less invasive spine surgery in one person with neuromuscular scoliosis, a severe spine curve caused by nerve or muscle problems. The goal was to see if the mini-invasive approach could reduce pain, blood loss, and complications compared to standard surgery. Th…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Symptom relief
Last updated Jun 27, 2026 09:08 UTC
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Can adding simple exercises boost back pain relief?
Symptom relief CompletedThis study looked at whether adding therapeutic exercises to a hands-on technique called positional release helps people with chronic low back pain more than the technique alone. Sixty adults aged 20-65 with ongoing back pain took part. Researchers measured pain, disability, and …
Sponsor: Palestine Ahliya University • Aim: Symptom relief
Last updated Jun 27, 2026 09:03 UTC
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Neck surgery pain relief: could a simple injection cut opioid use?
Symptom relief CompletedThis study tested whether a nerve block called an erector spinae plane block, given before cervical spine surgery, can reduce pain and the need for opioids afterward. Sixty adults undergoing neck fusion surgery were randomly assigned to receive either the anesthetic ropivacaine o…
Phase 4 • Sponsor: Poznan University of Medical Sciences • Aim: Symptom relief
Last updated Jun 27, 2026 09:01 UTC
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New exercise program aims to ease pain and fear after back surgery
Symptom relief CompletedThis study tested whether adding supervised motor control exercises to standard physical therapy helps people who had lumbar decompression surgery. Fifty-one volunteers were split into two groups: one got usual care (stretching, strengthening, and education), and the other got th…
Sponsor: Muğla Sıtkı Koçman University • Aim: Symptom relief
Last updated Jun 27, 2026 08:04 UTC
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New Ultrasound-Guided injection technique tested for back pain relief
Symptom relief CompletedThis pilot study tested whether using ultrasound to guide pharmacopuncture (herbal injections) is safe and effective for neck and back pain. Fifty adults with spinal disorders received the treatment, and researchers tracked side effects, pain levels, disability, and quality of li…
Sponsor: Jaseng Medical Foundation • Aim: Symptom relief
Last updated Jun 27, 2026 07:52 UTC
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Remote work may be reshaping our spines and screen habits
Knowledge-focused CompletedThis study looks at how working from home affects posture, neck and back pain, and internet use. Researchers will measure spine angles and muscle structure in adults who work remotely, and assess their internet addiction levels. The goal is to understand if increased screen time …
Sponsor: Hacettepe University • Aim: Knowledge-focused
Last updated Jul 17, 2026 00:00 UTC
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Spine surgery Patients' data collected to improve future care
Knowledge-focused CompletedThis study gathered information from 193 adults who had surgery or orthopedic treatment for spine problems. Researchers collected clinical, functional, and social data to create a detailed database. The goal was to better understand patient outcomes and standardize how data is co…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 14:00 UTC
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Spine scan showdown: MRI vs PET/CT – safety and clarity compared
Knowledge-focused CompletedThis study looked at 120 adults with neck or lower back spine issues to compare two types of scans: contrast-enhanced MRI and FDG-PET/CT. Researchers checked how clear the images were and whether the scans caused any short-term changes in kidney function or blood counts. The goal…
Sponsor: Cairo University • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:08 UTC
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New 3D X-Ray technique maps body alignment in posture disorders
Knowledge-focused CompletedThis completed study looked at how the skeleton is aligned with gravity in adults with postural problems. Researchers used a low-dose X-ray device called EOS to create 3D images of the spine and pelvis. The goal was to better understand the body's geometry in people with balance …
Sponsor: University Hospital, Bordeaux • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:38 UTC
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New device aims to cut spine screw errors in half
Knowledge-focused CompletedThis study tested a new lightweight device called PYTHEAS ODYSSEE that helps surgeons place screws in the spine more accurately. Fourteen adults having spine surgery used the device to guide screw placement. The goal was to see if the device reduces screw misplacement and is safe…
Sponsor: Centre Hospitalier Universitaire de Nīmes • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:23 UTC
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Nerve block vs. IV anesthesia: which saves more money in scoliosis surgery?
Knowledge-focused CompletedThis study looked at 44 people aged 12-25 having scoliosis surgery to see if a nerve block (ESP block) is more cost-effective than standard IV anesthesia. Researchers measured quality of life and healthcare costs shortly after surgery. The goal is to find out if the nerve block p…
Sponsor: National Bank Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:01 UTC
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Spine surgery movement analysis: a small step for better recovery
Knowledge-focused CompletedThis study looked at how the spine moves in 10 people with spinal tumors before and after vertebrectomy surgery. Researchers used motion analysis to measure walking, standing, and trunk movements. The goal was to better understand spine function and possibly improve future treatm…
Sponsor: Istituto Ortopedico Rizzoli • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:09 UTC
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Massive spine surgery database aims to unlock better treatments
Knowledge-focused CompletedThis study collected information from over 8,000 people who had spine surgery for conditions like degeneration, deformity, or trauma. Researchers gathered X-ray and health data to learn which treatments work best for different patients. The goal was to build a database to answer …
Sponsor: NuVasive • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:06 UTC
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Apple watch tracks spine surgery recovery in stanford study
Knowledge-focused CompletedThis study tested whether having spine surgery patients wear an Apple Watch could help doctors track their recovery. 255 adults wore the watch before and after surgery to measure steps and distance. The goal was to see if this data matched how patients felt and if it could improv…
Sponsor: Stanford University • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:05 UTC
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Routine x-rays after spinal fusion may be unnecessary, study suggests
Knowledge-focused CompletedThis study reviewed the records of 978 adults who had spinal fusion surgery to see how often routine follow-up X-rays led to additional tests or changes in treatment. The goal is to find out whether these X-rays are truly helpful or if they can be skipped. The results could help …
Sponsor: Universitaire Ziekenhuizen KU Leuven • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:53 UTC
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Herbal injections for pain: are they safe? large study investigates
Knowledge-focused CompletedThis completed study looked at the safety of pharmacopuncture—herbal extracts injected into acupuncture points—in 1,000 hospitalized adults with spine or joint problems. Researchers tracked infections and other side effects to see how often problems occur. The goal was to gather …
Sponsor: Jaseng Medical Foundation • Aim: Knowledge-focused
Last updated Jun 26, 2026 13:46 UTC