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Spinal surgery bleeding: which dose of TXA works best?

NCT ID NCT07288697

Completed Disease control Sponsor: Dr. Lutfi Kirdar Kartal Training and Research Hospital Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested two doses of the drug tranexamic acid (TXA) in 62 adults undergoing multilevel spinal surgery. The goal was to see which dose better reduces blood loss and the need for blood transfusions. Results could help surgeons choose the safest and most effective dose.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

tranexamic acid (TXA)

What this could lead to

If successful, this could help determine the best dose of tranexamic acid to reduce blood loss and transfusions during spinal surgery.

What could go wrong

This is a small, completed trial with only 62 participants. Results may not apply to all patients or surgeries, and dosing differences may not lead to clear benefits.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical Hemorrhage intervertebral disk degenerative disorder spondylosis vertebral column disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD LOSS, SURGICAL DEGENERATIVE SPINE DISEASE SPINAL DISORDERS

Contacts and locations

Locations

  • Kartal Dr. Lütfi Kırdar Şehir Hastanesi

    Istanbul, 34865, Turkey (Türkiye)