Which drug cuts C-Section bleeding best? tranexamic acid vs misoprostol put to the test

NCT ID NCT07712510

Completed Disease control Sponsor: Medicare Hospital (Pvt) Limited Source: ClinicalTrials.gov ↗

First seen Jul 17, 2026 · Last updated Jul 17, 2026

Summary

This trial compares two medicines—intravenous tranexamic acid and rectal misoprostol—for reducing blood loss in women having a planned cesarean section. About 214 women will be randomly assigned to receive one of the drugs before surgery. Researchers will measure blood loss during and two hours after the procedure, as well as changes in hemoglobin levels, to see which treatment is more effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: intravenous tranexamic acid or rectal misoprostol
What this could lead to: If one medicine works better, it could become the standard choice to reduce bleeding and prevent anemia after cesarean sections.
What could go wrong: This is a single-hospital study with 214 participants, so results may not apply to all women. Both drugs have side effects, and the trial does not track long-term outcomes.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Blood Loss, Surgical Postoperative Hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BLOOD LOSS, POSTOPERATIVE BLOOD LOSS, SURGICAL CESAREAN SECTION

Contacts and locations

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Locations

Medicare Hospital (Pvt) Limited

Multan, Punjab Province, 60000, Pakistan

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