Uveitis
MONDO:0020283An inflammatory process affecting a part of or the entire uvea. Causes include inflammatory agents (e.g., herpes simplex, herpes zoster, leptospirosis) and systemic diseases (e.g., inflammatory bowel disease, multiple sclerosis, systemic lupus erythematosus, ankylosing spondylitis). Patients present with pain and redness in the eye, light sensitivity, and blurred and decreased vision.
Also known as: inflammation of uvea, uvea inflammation, uveitis, uveitis (disease)
78 clinical trials for this condition and its sub-types.
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Broader categories
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New hope for kids with eye inflammation: baricitinib trial shows promise
Disease control OngoingThis study tests whether baricitinib, an oral drug, is safe and effective for children aged 2 to 18 with active uveitis (eye inflammation) linked to juvenile arthritis or a related condition. Participants had not responded well to standard treatments. The main goal is to reduce e…
Phase: PHASE3 • Sponsor: Eli Lilly and Company • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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Experimental antibody takes aim at eye inflammation
Disease control OngoingThis study tests an experimental drug called REGN7041 in 72 people with active noninfectious uveitis, a condition causing inflammation inside the eye. The drug is an antibody designed to calm the immune system. Since this is the first time it's tested in humans, the main goal is …
Phase: PHASE1, PHASE2 • Sponsor: Regeneron Pharmaceuticals • Aim: Disease control
Last updated Jun 27, 2026 12:23 UTC
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New pill could tame debilitating eye inflammation, major trial underway
Disease control OngoingThis study tests an oral medication called brepocitinib in adults with active uveitis, a condition causing inflammation inside the eye. The goal is to see if the drug can prevent the disease from worsening and help maintain vision. About 371 participants will receive either the d…
Phase: PHASE3 • Sponsor: Priovant Therapeutics, Inc. • Aim: Disease control
Last updated Jun 27, 2026 08:10 UTC
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Pharmacists take on heart disease: new study tests community-based risk reduction
Disease control OngoingThis study tests whether a pharmacist-led program can help people reduce their risk of heart disease. Over 1,000 adults with conditions like diabetes, high blood pressure, or obesity are taking part. Pharmacists use a step-by-step guide to assess risk and support lifestyle change…
Phase: NA • Sponsor: University of Alberta • Aim: Disease control
Last updated Jun 27, 2026 08:08 UTC
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NIH launches Long-Term observation of inflammatory diseases
Knowledge-focused ENROLLING_BY_INVITATIONThis study follows up to 500 people with acute or chronic inflammatory disorders, such as infections or immune problems, over time. Researchers will monitor participants with standard tests and may screen them for other studies. The goal is to better understand these conditions a…
Sponsor: National Institute of Allergy and Infectious Diseases (NIAID) • Aim: Knowledge-focused
Last updated Jul 04, 2026 00:00 UTC
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Scientists hunt for genetic clues in blood and urine to personalize lung cancer care
Knowledge-focused OngoingThis study collects blood, urine, and tissue samples from 330 adults with advanced lung or head and neck cancer to improve precision medicine. Researchers will analyze genetic changes in these samples and grow some tumors in mice to compare DNA. The goal is to refine liquid biops…
Phase: NA • Sponsor: University of Arkansas • Aim: Knowledge-focused
Last updated Jun 27, 2026 13:00 UTC
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New eye software could sharpen inflammation detection
Knowledge-focused OngoingThis study is testing a new software that measures eye inflammation from standard images taken during routine care. Researchers will enroll 50 people with uveitis, an inflammatory eye disease, to see if the software can detect meaningful changes in inflammation. The goal is to he…
Sponsor: The Cleveland Clinic • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:10 UTC
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Eye fluid test may personalize uveitis treatment
Knowledge-focused OngoingThis study tests whether analyzing fluid from the eye can predict which immunosuppressive drug will work best for people with non-infectious uveitis, an eye inflammation condition. About 220 participants who haven't responded well to steroids will provide eye fluid and blood samp…
Phase: NA • Sponsor: University of Milan • Aim: Knowledge-focused
Last updated Jun 27, 2026 08:01 UTC
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Free eye tests aim to catch vision loss early in harlem and washington heights
Knowledge-focused OngoingThis study offers free vision screenings to underserved adults over 40 living in affordable housing in Harlem and Washington Heights. The goal is to find eye problems like glaucoma, cataracts, and diabetic retinopathy early and connect people with follow-up care. About 749 partic…
Phase: NA • Sponsor: Columbia University • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:54 UTC
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Singapore eye study aims to uncover patterns in inflammatory eye diseases
Knowledge-focused OngoingThis study reviews medical records of 200 people in Singapore with inflammatory eye diseases like uveitis and scleritis. Researchers want to understand who gets these conditions, what treatments they receive, and how they do over time. No new treatments are being tested—this is p…
Sponsor: Singapore National Eye Centre • Aim: Knowledge-focused
Last updated Jun 26, 2026 18:36 UTC