Eye fluid test may personalize uveitis treatment

NCT ID NCT07262437

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether analyzing fluid from the eye can predict which immunosuppressive drug will work best for people with non-infectious uveitis, an eye inflammation condition. About 220 participants who haven't responded well to steroids will provide eye fluid and blood samples. Researchers will measure immune signals in the fluid and compare them to how patients respond to standard drugs like methotrexate or adalimumab. The goal is to make treatment more personalized and effective.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to

If successful, this could help doctors choose the right immunosuppressive drug for each uveitis patient, improving treatment outcomes.

What could go wrong

This is an observational study, not a treatment trial. It may not lead to immediate changes in care, and results might not apply to all patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anterior uveitis endophthalmitis Inflammation posterior uveitis uveitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • ASST Fatebenefratelli Sacco P.O.L.Sacco

    Milan, 20157, Italy

  • AUSL Reggio Emilia

    Reggio Emilia, 42122, Italy

  • IRCCS San Raffaele Università Vita e Salute

    Milan, 20132, Italy