New drug aims to tame eye inflammation in uveitis patients
NCT ID NCT07547995
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug, GenSci048, in people with active non-infectious uveitis, an inflammatory eye disease. The trial will compare two doses of GenSci048 against a placebo to see if it can control the disease and reduce treatment failure. About 111 adults with active uveitis will participate, and the main goal is to measure how many avoid worsening of their condition over 25 weeks.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
GenSci048
What this could lead to
If successful, this could provide a new treatment option to control active non-infectious uveitis, potentially reducing the need for high-dose steroids.
What could go wrong
This is an early Phase 2 trial with only 111 participants, so results may not apply to all patients. The drug may not prove more effective than placebo, and side effects are still being studied.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Eye & Ent Hospital of Fudan University
Shanghai, Shanghai Municipality, 200031, China