Soft tissue sarcoma
MONDO:0018078A malignant neoplasm arising from muscle tissue, adipose tissue, blood vessels, fibrous tissue, or other supportive tissues excluding the bones.
Also known as: malignant soft tissue tumor, malignant soft tissue tumour, connective tissue sarcoma, malignant mesenchymal tumor, malignant mesenchymal tumour, non-Rhabdo. soft tissue sarcoma, sarcoma of soft tissue, sarcoma of the soft tissue
3374 clinical trials for this condition and its sub-types, 297 tagged with Soft tissue sarcoma itself.
Follow this condition to get notified about new trialsWhere it sits in the disease tree
Browse by category →Sub-types of Soft tissue sarcoma
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Rhabdomyosarcoma 100 trials · 114 incl. sub-types
20 sub-types
- Alveolar rhabdomyosarcoma 9 trials
- Pleomorphic rhabdomyosarcoma 7 trials Sub-types →
- Embryonal rhabdomyosarcoma 4 trials Sub-types →
- Spindle cell rhabdomyosarcoma 3 trials Sub-types →
- Testis rhabdomyosarcoma 1 trial
- Breast rhabdomyosarcoma 0 trials
- Central nervous system rhabdomyosarcoma 0 trials
- Gallbladder rhabdomyosarcoma 0 trials
- Liver rhabdomyosarcoma 0 trials Sub-types →
- Mediastinum rhabdomyosarcoma 0 trials
- Oral rhabdomyosarcoma 0 trials
- Orbit rhabdomyosarcoma 0 trials Sub-types →
- Ovary rhabdomyosarcoma 0 trials
- Prostate rhabdomyosarcoma 0 trials Sub-types →
- Rectum rhabdomyosarcoma 0 trials Sub-types →
- Rhabdomyosarcoma of the cervix uteri 0 trials
- Rhabdomyosarcoma with mixed embryonal and alveolar features 0 trials
- Rhabdomyosarcoma, embryonal, 2 0 trials
- Uterine corpus rhabdomyosarcoma 0 trials
- Vaginal rhabdomyosarcoma 0 trials Sub-types →
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Liposarcoma 58 trials · 83 incl. sub-types
19 sub-types
- Dedifferentiated liposarcoma 37 trials
- Myxoid/round cell liposarcoma 13 trials · 18 incl. sub-types Sub-types →
- Pleomorphic liposarcoma 8 trials
- Well-differentiated liposarcoma 5 trials Sub-types →
- Adult liposarcoma 0 trials
- Breast liposarcoma 0 trials
- Cutaneous liposarcoma 0 trials
- Esophagus liposarcoma 0 trials
- Fibroblastic liposarcoma 0 trials
- Gastric liposarcoma 0 trials
- Intracranial liposarcoma 0 trials
- Kidney liposarcoma 0 trials
- Larynx liposarcoma 0 trials
- Liposarcoma of bone 0 trials
- Liposarcoma of the ovary 0 trials Sub-types →
- Mediastinum liposarcoma 0 trials
- Mixed liposarcoma 0 trials
- Pediatric liposarcoma 0 trials
- Vulvar liposarcoma 0 trials
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Angiosarcoma 37 trials · 82 incl. sub-types
19 sub-types
- Kaposi's sarcoma 45 trials Sub-types →
- Skin angiosarcoma 6 trials
- Breast angiosarcoma 1 trial
- Angiosarcoma of the scalp 0 trials
- Aorta angiosarcoma 0 trials
- Bone angiosarcoma 0 trials
- Central nervous system angiosarcoma 0 trials
- Conventional angiosarcoma 0 trials
- Gallbladder angiosarcoma 0 trials
- Liver angiosarcoma 0 trials
- Mediastinum angiosarcoma 0 trials
- Ovarian angiosarcoma 0 trials
- Pediatric angiosarcoma 0 trials
- Prostate angiosarcoma 0 trials
- Pulmonary artery leiomyosarcoma 0 trials
- Pulmonary vein leiomyosarcoma 0 trials
- Spleen angiosarcoma 0 trials
- Superior vena cava angiosarcoma 0 trials Sub-types →
- Thyroid gland angiosarcoma 0 trials
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Rhabdoid tumor 63 trials · 75 incl. sub-types
5 sub-types
- Atypical teratoid rhabdoid tumor 35 trials · 36 incl. sub-types Sub-types →
- Rhabdoid tumor of the kidney 7 trials
- Extrarenal rhabdoid tumor 1 trial
- Familial rhabdoid tumor 0 trials · 1 incl. sub-types Sub-types →
- Striated muscle rhabdoid tumor 0 trials
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Central nervous system sarcoma 2 trials · 74 incl. sub-types
12 sub-types
- Malignant peripheral nerve sheath tumor 36 trials · 38 incl. sub-types Sub-types →
- Atypical teratoid rhabdoid tumor 35 trials · 36 incl. sub-types Sub-types →
- Brain sarcoma 0 trials Sub-types →
- Central nervous system angiosarcoma 0 trials
- Central nervous system extraskeletal osteosarcoma 0 trials
- Central nervous system fibrosarcoma 0 trials
- Central nervous system leiomyosarcoma 0 trials Sub-types →
- Central nervous system rhabdomyosarcoma 0 trials
- Intracranial extraskeletal myxoid chondrosarcoma 0 trials
- Isolated melanotic schwannoma 0 trials
- Meningeal sarcoma 0 trials Sub-types →
- Spinal cord sarcoma 0 trials
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Leiomyosarcoma 62 trials · 72 incl. sub-types
31 sub-types
- Leiomyosarcoma of the corpus uteri 9 trials Sub-types →
- Ovary leiomyosarcoma 2 trials
- Retroperitoneal leiomyosarcoma 2 trials
- Inflammatory leiomyosarcoma 1 trial
- Small intestine leiomyosarcoma 1 trial
- Bone leiomyosarcoma 0 trials
- Breast leiomyosarcoma 0 trials
- Central nervous system leiomyosarcoma 0 trials Sub-types →
- Colon leiomyosarcoma 0 trials
- Conventional leiomyosarcoma 0 trials
- Cutaneous leiomyosarcoma 0 trials
- Epithelioid leiomyosarcoma 0 trials Sub-types →
- Esophagus leiomyosarcoma 0 trials
- Fallopian tube leiomyosarcoma 0 trials
- Gallbladder leiomyosarcoma 0 trials
- Gastric leiomyosarcoma 0 trials
- Heart leiomyosarcoma 0 trials
- Kidney leiomyosarcoma 0 trials
- Laryngeal leiomyosarcoma 0 trials
- Leiomyosarcoma of the cervix uteri 0 trials
- Liver leiomyosarcoma 0 trials Sub-types →
- Lung leiomyosarcoma 0 trials
- Mediastinum leiomyosarcoma 0 trials
- Myxoid leiomyosarcoma 0 trials Sub-types →
- Prostate leiomyosarcoma 0 trials
- Pulmonary artery leiomyosarcoma 0 trials
- Pulmonary vein leiomyosarcoma 0 trials
- Rectum leiomyosarcoma 0 trials Sub-types →
- Superior vena cava leiomyosarcoma 0 trials
- Vagina leiomyosarcoma 0 trials
- Vulvar leiomyosarcoma 0 trials
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Synovial sarcoma 53 trials
5 sub-types
- Biphasic synovial sarcoma 0 trials
- Breast synovial sarcoma 0 trials
- Fibrous synovial sarcoma 0 trials
- Mediastinum synovial sarcoma 0 trials
- Monophasic synovial sarcoma 0 trials Sub-types →
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Undifferentiated pleomorphic sarcoma 48 trials
3 sub-types
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Desmoplastic small round cell tumor 26 trials
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Myxofibrosarcoma 21 trials
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Fibrosarcoma 9 trials · 21 incl. sub-types
11 sub-types
- Dermatofibrosarcoma protuberans 11 trials Sub-types →
- Low grade fibromyxoid sarcoma 4 trials Sub-types →
- Conventional fibrosarcoma 0 trials · 2 incl. sub-types Sub-types →
- Pediatric fibrosarcoma 0 trials · 2 incl. sub-types Sub-types →
- Bone fibrosarcoma 0 trials
- Breast fibrosarcoma 0 trials
- Central nervous system fibrosarcoma 0 trials
- Heart fibrosarcoma 0 trials
- Kidney fibrosarcoma 0 trials
- Liver fibrosarcoma 0 trials
- Small intestinal fibrosarcoma 0 trials
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Alveolar soft part sarcoma 20 trials
2 sub-types
- Cervical alveolar soft part sarcoma 0 trials
- Vulvar alveolar soft part sarcoma 0 trials
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Epithelioid sarcoma 20 trials
4 sub-types
- Adult epithelioid sarcoma 0 trials
- Childhood epithelioid sarcoma 0 trials
- Peripheral epithelioid sarcoma 0 trials
- Proximal-type epithelioid sarcoma 0 trials Sub-types →
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Retroperitoneal sarcoma 17 trials
1 sub-type
- Retroperitoneal leiomyosarcoma 2 trials
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Clear cell sarcoma 14 trials · 16 incl. sub-types
1 sub-type
- Clear cell sarcoma of kidney 2 trials
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Liver sarcoma 1 trial · 10 incl. sub-types
7 sub-types
- Undifferentiated (embryonal) sarcoma 9 trials
- Bile duct sarcoma 0 trials Sub-types →
- Liver angiosarcoma 0 trials
- Liver extraskeletal osteosarcoma 0 trials
- Liver fibrosarcoma 0 trials
- Liver leiomyosarcoma 0 trials Sub-types →
- Liver rhabdomyosarcoma 0 trials Sub-types →
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Skin sarcoma 1 trial · 9 incl. sub-types
5 sub-types
- Skin angiosarcoma 6 trials
- Cutaneous undifferentiated pleomorphic sarcoma 2 trials
- Cutaneous leiomyosarcoma 0 trials
- Cutaneous liposarcoma 0 trials
- Skin lymphangiosarcoma 0 trials
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SMARCA4-deficient sarcoma of thorax 8 trials
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Kidney sarcoma 0 trials · 8 incl. sub-types
7 sub-types
- Rhabdoid tumor of the kidney 7 trials
- Clear cell sarcoma of kidney 2 trials
- Anaplastic sarcoma of the kidney 0 trials
- Kidney fibrosarcoma 0 trials
- Kidney leiomyosarcoma 0 trials
- Kidney liposarcoma 0 trials
- Kidney osteogenic sarcoma 0 trials
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Extraskeletal myxoid chondrosarcoma 7 trials
1 sub-type
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Intimal sarcoma 4 trials
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Extraskeletal Ewing sarcoma 3 trials
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Undifferentiated round cell sarcoma 3 trials
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Breast sarcoma 2 trials · 3 incl. sub-types
7 sub-types
- Breast angiosarcoma 1 trial
- Breast extraskeletal osteosarcoma 0 trials
- Breast fibrosarcoma 0 trials
- Breast leiomyosarcoma 0 trials
- Breast liposarcoma 0 trials
- Breast rhabdomyosarcoma 0 trials
- Breast synovial sarcoma 0 trials
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Extraosseous osteosarcoma 2 trials
7 sub-types
- Adult extraskeletal osteosarcoma 0 trials
- Breast extraskeletal osteosarcoma 0 trials
- Central nervous system extraskeletal osteosarcoma 0 trials
- Childhood extraosseous osteosarcoma 0 trials
- Kidney osteogenic sarcoma 0 trials
- Liver extraskeletal osteosarcoma 0 trials
- Mediastinal extraskeletal osteosarcoma 0 trials
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Ovarian sarcoma 0 trials · 2 incl. sub-types
4 sub-types
- Ovary leiomyosarcoma 2 trials
- Liposarcoma of the ovary 0 trials Sub-types →
- Ovarian angiosarcoma 0 trials
- Ovary rhabdomyosarcoma 0 trials
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Heart sarcoma 1 trial
3 sub-types
- Heart fibrosarcoma 0 trials
- Heart leiomyosarcoma 0 trials
- Malignant cardiac peripheral nerve sheath neoplasm 0 trials
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Small intestinal sarcoma 0 trials · 1 incl. sub-types
2 sub-types
- Small intestine leiomyosarcoma 1 trial
- Small intestinal fibrosarcoma 0 trials
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Testis sarcoma 0 trials · 1 incl. sub-types
1 sub-type
- Testis rhabdomyosarcoma 1 trial
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Anus sarcoma 0 trials
2 sub-types
- Anus leiomyosarcoma 0 trials
- Anus rhabdomyosarcoma 0 trials
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Bladder sarcoma 0 trials
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Esophagus sarcoma 0 trials
2 sub-types
- Esophagus leiomyosarcoma 0 trials
- Esophagus liposarcoma 0 trials
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Gallbladder sarcoma 0 trials
3 sub-types
- Gallbladder angiosarcoma 0 trials
- Gallbladder leiomyosarcoma 0 trials
- Gallbladder rhabdomyosarcoma 0 trials
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Laryngeal sarcoma 0 trials
2 sub-types
- Laryngeal leiomyosarcoma 0 trials
- Larynx liposarcoma 0 trials
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Lung sarcoma 0 trials
1 sub-type
- Lung leiomyosarcoma 0 trials
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Mediastinum sarcoma 0 trials
7 sub-types
- Malignant melanocytic peripheral nerve sheath tumor of mediastinum 0 trials
- Mediastinal extraskeletal osteosarcoma 0 trials
- Mediastinum angiosarcoma 0 trials
- Mediastinum leiomyosarcoma 0 trials
- Mediastinum liposarcoma 0 trials
- Mediastinum rhabdomyosarcoma 0 trials
- Mediastinum synovial sarcoma 0 trials
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Myxosarcoma 0 trials
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Pancreas sarcoma 0 trials
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Paranasal sinus sarcoma 0 trials
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Penile sarcoma 0 trials
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Prostate sarcoma 0 trials
4 sub-types
- Prostate angiosarcoma 0 trials
- Prostate leiomyosarcoma 0 trials
- Prostate rhabdomyosarcoma 0 trials Sub-types →
- Prostate stromal sarcoma 0 trials
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Stromal sarcoma 0 trials
1 sub-type
- Prostate stromal sarcoma 0 trials
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Thyroid sarcoma 0 trials
1 sub-type
- Thyroid gland angiosarcoma 0 trials
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Trachea sarcoma 0 trials
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Vagina sarcoma 0 trials
3 sub-types
- Endometrioid stromal sarcoma of the vagina 0 trials
- Vagina leiomyosarcoma 0 trials
- Vaginal rhabdomyosarcoma 0 trials Sub-types →
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Vulva sarcoma 0 trials
5 sub-types
- Vulvar alveolar soft part sarcoma 0 trials
- Vulvar childhood botryoid-type embryonal rhabdomyosarcoma 0 trials
- Vulvar leiomyosarcoma 0 trials
- Vulvar liposarcoma 0 trials
- Vulvar proximal-type epithelioid sarcoma 0 trials
Most studied deeper sub-types
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Can Pre-Surgery chemo boost outcomes in High-Risk Soft-Tissue sarcoma?
Disease control Not yet recruitingThis phase 3 trial compares adding doxorubicin and ifosfamide (AIM chemotherapy) before standard treatment with pembrolizumab, radiation therapy, and surgery versus standard treatment alone in patients with high-risk soft-tissue sarcomas that can be removed by surgery. Participan…
Phase 3 • Sponsor: Ohio State University Comprehensive Cancer Center • Aim: Disease control
Last updated Sep 18, 2026 00:00 UTC
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Can a Dual-Target drug crack resistant gynecologic and breast cancers?
Disease control Not yet recruitingResearchers are testing an oral drug called AL58805, which blocks two cancer-growth proteins, PI3K and mTOR, in adults with advanced endometrial, cervical, soft tissue sarcoma, or breast cancers that have worsened after at least one standard treatment. Participants receive AL5880…
Phase 1/2 • Sponsor: Advenchen Pharmaceuticals, LLC. • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Can an oral drug that starves tumors help Hard-to-Treat cancers?
Disease control Not yet recruitingResearchers are testing an investigational oral drug called catequentinib hydrochloride (AL3818) in adults with advanced or metastatic endometrial cancer, low grade serous ovarian cancer, soft tissue sarcoma, or glioblastoma. The trial has two parts: a phase 1b part to find safe …
Phase 1/2 • Sponsor: Advenchen Pharmaceuticals, LLC. • Aim: Disease control
Last updated Sep 12, 2026 00:00 UTC
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Can a smart drug hunt down sarcoma cells without harming healthy ones?
Disease control Not yet recruitingThis trial tests SOT106, a cancer medicine designed to find and kill cells that carry a marker called LRRC15, which appears on some osteosarcoma and soft tissue sarcoma tumors. The study has two parts: the first finds safe dose levels, and the second compares two doses to see whi…
Phase 1/2 • Sponsor: SOTIO Biotech a.s. • Aim: Disease control
Last updated Sep 05, 2026 00:00 UTC
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Can a Patient's own immune cells fight advanced sarcoma?
Disease control Not yet recruitingThis phase 2 trial is testing whether lifileucel, a therapy made from a patient's own tumor-infiltrating lymphocytes (immune cells), can shrink tumors in adults with advanced soft tissue sarcoma. Participants will have their tumor removed to create the personalized therapy, then …
Phase 2 • Sponsor: Iovance Biotherapeutics, Inc. • Aim: Disease control
Last updated Aug 05, 2026 00:00 UTC
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New drug combo aims to fight rare sarcoma
Disease control Not yet recruitingThis Phase 2 trial tests two drugs, OVV-01 and AK112, given together every two weeks to 40 adults with advanced soft tissue sarcoma that has not responded to standard treatments. The main goal is to see if the combination can shrink tumors safely. Researchers will also measure ho…
Phase 2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 14:00 UTC
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Could a saffron-derived compound boost radiation for sarcoma?
Disease control Not yet recruitingThis phase 2 trial tests whether adding a drug called liposomal transcrocetin (L-TC) to short-course radiation before surgery can kill more cancer cells in people with soft-tissue sarcoma. About 42 adults with localized or locally advanced sarcoma will be randomly assigned to rec…
Phase 2 • Sponsor: Centre Paul Strauss • Aim: Disease control
Last updated Jun 27, 2026 13:02 UTC
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Could 5 days of radiation replace 25 for sarcoma patients?
Disease control Not yet recruitingThis study compares a short course of radiation therapy (5 days) to the standard longer course (25 days) for people with soft tissue sarcoma in the arms or legs that can be removed with surgery. The goal is to see if the shorter treatment is just as effective at preventing the ca…
Phase 3 • Sponsor: SWOG Cancer Research Network • Aim: Disease control
Last updated Jun 27, 2026 13:00 UTC
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Could adding immunotherapy to Pre-Sarcoma treatment boost survival?
Disease control Not yet recruitingThis study looks at whether adding an immunotherapy drug (penpulimab) to standard pre-surgery radiation and a targeted therapy (anlotinib) can help people with soft tissue sarcoma live longer without the cancer coming back. About 274 adults with intermediate- to high-grade sarcom…
Phase 2 • Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 12:39 UTC
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New mRNA shot targets Hard-to-Treat cancers in early human test
Disease control Not yet recruitingThis early-phase study tests a new mRNA medicine (NCP-IL-22BP mRNA) in 9 people with advanced solid tumors that have not responded to standard treatments. The medicine is injected directly into tumors to help the body fight cancer. The main goal is to check safety and find the ri…
Phase 1 • Sponsor: West China Hospital • Aim: Disease control
Last updated Jun 27, 2026 12:32 UTC
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Iron nanoparticles could supercharge radiation against cancer
Disease control Not yet recruitingThis Phase 2 trial tests an experimental iron nanoparticle injection (CNSI-Fe) given directly into tumors along with standard radiotherapy. The goal is to see if the combination shrinks tumors better than radiation alone. The study will enroll 52 adults with head and neck cancer …
Phase 2 • Sponsor: Sichuan Enray Pharmaceutical Sciences Company • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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New drug cocktail aims to halt sarcoma progression
Disease control Not yet recruitingThis phase 2 trial tests a combination of three drugs—liposomal irinotecan, temozolomide, and bevacizumab—in 24 people with soft tissue sarcoma that has returned or not responded to prior treatment. The goal is to see if the combination can slow or stop tumor growth. Participants…
Phase 2 • Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University • Aim: Disease control
Last updated Jun 27, 2026 11:00 UTC
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Engineered t cells take on Hard-to-Treat cancers in new trial
Disease control Not yet recruitingThis early-stage study tests a new treatment for people with advanced ovarian cancer or other solid tumors that have come back or not responded to standard therapy. The treatment uses a patient's own immune cells that are genetically modified to better recognize and attack cancer…
Phase 1/2 • Sponsor: University of Chicago • Aim: Disease control
Last updated Jun 27, 2026 09:07 UTC
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New combo therapy aims to improve sarcoma surgery outcomes
Disease control Not yet recruitingThis trial is testing whether giving a special type of radiation (ultra-hypofractionated) along with immunotherapy before surgery is safe and feasible for people with retroperitoneal sarcoma. The study will enroll 28 participants. The main goal is to see how many patients have co…
Sponsor: Cancer Institute and Hospital, Chinese Academy of Medical Sciences • Aim: Disease control
Last updated Jun 27, 2026 09:05 UTC
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Can a nose ointment and body wash prevent surgery wounds from getting worse?
Disease control Not yet recruitingThis study tests if using a nose ointment and body wash before and during radiation, plus a special dye during surgery, can lower the chance of serious wound problems. About 31 people with soft tissue sarcoma in the leg will take part. The goal is to see if these low-cost steps h…
Phase 2 • Sponsor: Adam Olson • Aim: Disease control
Last updated Jun 27, 2026 09:03 UTC
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New combo therapy aims to tackle tough sarcomas
Disease control Not yet recruitingThis phase 2 trial is testing a new treatment for soft tissue sarcoma that combines a special type of radiation with immunotherapy and immune-boosting drugs. The goal is to see if this combination can shrink tumors and improve outcomes for people with advanced or recurrent sarcom…
Phase 2 • Sponsor: First Affiliated Hospital of Guangxi Medical University • Aim: Disease control
Last updated Jun 27, 2026 08:11 UTC
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Experimental drug combo takes on rare sarcomas
Disease control Not yet recruitingThis early-phase trial tests a new drug called BOLD-100 combined with standard chemotherapy (doxorubicin) in 32 people with advanced soft tissue sarcomas that cannot be removed by surgery or have spread. The goal is to find the safest dose and see if the combination can shrink tu…
Phase 1 • Sponsor: University Health Network, Toronto • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New radiation approach aims to improve sarcoma surgery outcomes
Disease control Not yet recruitingThis study tests a new type of radiation called carbon ion radiotherapy given before surgery for soft tissue sarcoma. The goal is to see if it is safe and can reduce wound problems after surgery while better controlling the tumor. About 60 adults with sarcoma that can be removed …
Sponsor: Yonsei University • Aim: Disease control
Last updated Jun 27, 2026 08:00 UTC
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New cocktail of drugs and radiation targets Hard-to-Treat sarcoma
Disease control Not yet recruitingThis phase 2 trial tests a combination of the immunotherapy epalrotokewali, chemotherapy eribulin, targeted therapy anlotinib, and radiotherapy in 46 people with advanced soft tissue sarcoma that has progressed after prior treatment. The goal is to see if this mix can shrink tumo…
Phase 2 • Sponsor: Fudan University • Aim: Disease control
Last updated Jun 27, 2026 07:53 UTC
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New cocktail of drugs and radiation takes on Hard-to-Treat sarcoma
Disease control Not yet recruitingThis phase 2 trial tests whether combining two drugs (anlotinib and bempegaldesleukin) with standard radiation and chemotherapy can shrink or control advanced soft tissue sarcoma that cannot be surgically removed. About 46 adults aged 18 to 80 will receive the treatment in two ph…
Phase 2 • Sponsor: The First Affiliated Hospital with Nanjing Medical University • Aim: Disease control
Last updated Jun 26, 2026 14:22 UTC
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Smartwatch exercise plan aims to rebuild fitness in young cancer survivors
Symptom relief Not yet recruitingThis trial tests whether a personalized, smartwatch-supported home exercise program can increase physical activity and improve heart health, mobility, and quality of life in adolescents and young adults who have survived bone or soft tissue sarcoma. Participants wear a fitness tr…
Sponsor: Universität Duisburg-Essen • Aim: Symptom relief
Last updated Jul 29, 2026 00:00 UTC
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AI chatbot aims to ease anxiety for sarcoma patients
Symptom relief Not yet recruitingThis study is testing a new AI chatbot designed to answer questions from people with sarcoma, a type of cancer. The chatbot will be available 24/7 by voice or text for one month. Researchers want to see if using the chatbot helps patients feel more satisfied with the information …
Sponsor: The Hong Kong Polytechnic University • Aim: Symptom relief
Last updated Jun 27, 2026 12:01 UTC
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Can a few days of radiation before sarcoma surgery reduce complications?
Knowledge-focused Not yet recruitingThis study looks at whether a very short course of radiation (ultra-hypofractionated) given before surgery is safe and works well for people with soft tissue sarcoma in the arms, legs, or trunk. About 142 adults with low-to-medium risk sarcoma will be randomly assigned to receive…
Sponsor: Italian Sarcoma Group • Aim: Knowledge-focused
Last updated Sep 04, 2026 00:00 UTC
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Glow-in-the-dark dye may help surgeons spot sarcoma during removal
Knowledge-focused Not yet recruitingThis early-stage study tests whether a fluorescent dye called 5-ALA can make soft-tissue sarcoma tumors glow during surgery, helping surgeons see the edges more clearly. About 20 adults with grade 2 or 3 sarcoma will take the dye by mouth before their standard surgery. The main g…
Early phase 1 • Sponsor: University of Colorado, Denver • Aim: Knowledge-focused
Last updated Jul 24, 2026 00:00 UTC
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Tiny study checks if extra MRIs during sarcoma radiation are doable
Knowledge-focused Not yet recruitingThis very small study will test whether it is practical to add three extra MRI scans during standard radiation treatment for soft tissue sarcoma. Only 5 adults will take part. The goal is simply to see if the extra scans can be completed, not to change treatment or improve outcom…
Sponsor: Andrew Frankart • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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New blood test could spot sarcoma cells early
Knowledge-focused Not yet recruitingThis study aims to create a new method to find and sort cancer cells that float in the blood of people with advanced soft tissue sarcoma. Researchers will collect blood and tumor samples from 100 adults to develop this detection technique. The goal is to better understand the dis…
Sponsor: Centre Leon Berard • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:03 UTC
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Gut check: could your microbiome predict fertility after immunotherapy?
Knowledge-focused Not yet recruitingThis observational study looks at how immune checkpoint inhibitors (a type of cancer immunotherapy) affect ovarian function and fertility in women aged 18-38 with solid tumors. Researchers will collect blood and stool samples before and during treatment to measure hormone levels …
Sponsor: West China Second University Hospital • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:52 UTC