Iron nanoparticles could supercharge radiation against cancer

NCT ID NCT07491783

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase 2 trial tests an experimental iron nanoparticle injection (CNSI-Fe) given directly into tumors along with standard radiotherapy. The goal is to see if the combination shrinks tumors better than radiation alone. The study will enroll 52 adults with head and neck cancer or soft tissue sarcoma who are candidates for radiation therapy.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

carbon nanoparticle iron suspension (CNSI-Fe)

What this could lead to

If it works, this could offer a new way to boost radiotherapy's effect on solid tumors, potentially shrinking tumors more effectively.

What could go wrong

This is an early Phase 2 trial with only 52 people, so results may not apply widely. The injection is experimental and could cause side effects like pain or swelling at the injection site.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck squamous cell carcinoma sarcoma soft tissue sarcoma Squamous Cell Carcinoma of Head and Neck

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • West China Hospital, Sichuan University

    Chengdu, Sichuan, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact