New blood test could spot sarcoma cells early
NCT ID NCT07401355
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to create a new method to find and sort cancer cells that float in the blood of people with advanced soft tissue sarcoma. Researchers will collect blood and tumor samples from 100 adults to develop this detection technique. The goal is to better understand the disease and potentially improve future monitoring.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 100 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Mar 2026
An estimate. Start dates often move.
- Expected to finish
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Jan 2030
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Male or female patients ≥ 18 years at the day of consenting; * Histologically confirmed diagnosis of Soft Tissue Sarcoma (STS) excepted GIST. * Metastatic disease or unresectable locally advanced malignancy for which standard therapy by anthracycline is decided; * At least one measurable lesion as per RECIST version 1.1.; * ECOG Performance Status of 0-2; * Patients must have an adequate organ and bone marrow function at baseline; * Patient should understand, sign, and date the written voluntary informed consent form prior to any protocol-specific procedures performed and should be able and willing to comply with procedures as per protocol; * Covered by a medical insurance. Exclusion Criteria: * Evidence of significant uncontrolled concomitant disease that could affect compliance with the protocol or interpretation of results; * Prior treatment with anthracycline; * History of other malignancy other than study disease (except for basal cell or squamous cell carcinoma of the skin or carcinoma in situ of the cervix) unless the patient has been free of disease for at least 3 years; * Metabolic syndrome; * Pregnant or breast-feeding woman criteria
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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BRAHMI Mehdi
Lyon, 69008, France