Sexual disorder

This study will test whether living in a self-contained, AI-managed community (called a Microcity) can improve mental health and reduce addiction in adults with conditions like autism, ADHD, substance use disorders, and behavioral addictions. Up to 1 million participants will liv…

This study tests two different stitching techniques for closing the uterus after a planned C-section. One method includes the inner lining of the uterus in the stitch, the other leaves it out. Researchers will use ultrasound 6 to 9 months later to see which method leads to fewer …

This study tests two injection treatments for men with lifelong premature ejaculation that hasn't improved with standard drugs or therapy. Eighty men will receive either hyaluronic acid into the penis head or botox into a pelvic muscle. Researchers will track changes in ejaculati…

This trial tests whether a single injection of platelet-rich plasma (PRP), made from a woman's own blood, can reduce pain and improve healing after perineal tears or episiotomies during vaginal birth. About 160 women will receive either PRP or a placebo injection right after deli…

This trial tests whether an experimental drug called VV913 can help men with premature ejaculation last longer during intercourse. About 500 men aged 18 to 55 with diagnosed premature ejaculation will take either VV913 (at one of three doses) or a placebo pill before sex. Researc…

This trial tests F-GYN, a single-use injectable gel made of non-crosslinked hyaluronic acid, for women with moderate to severe vaginal dryness and atrophy. Participants either receive the injection right away or continue standard non-hormonal care for 4 weeks before getting the i…

This study looks at whether adding the drug bupropion (Wellbutrin) to standard hormone therapy can help women with early-stage breast cancer who have lost interest in sex. About 100 women will be randomly assigned to receive either their usual hormone therapy alone or with buprop…

This study compares two vaginal treatments—estrogen and DHEA—for relieving menopause symptoms like vaginal dryness, discomfort, and painful intercourse. About 324 women aged 40-90 will use one of the treatments and report changes in symptoms and sexual health. The goal is to help…

This study tests whether a specific set of pelvic floor exercises (called Exercise G128) can help men with erectile dysfunction, urinary incontinence, or premature ejaculation. One hundred men aged 18 to 60 will do the exercises four times a week for one month and have bi-weekly …

This study will test whether pelvic floor-focused clinical Pilates exercises can reduce pain, improve self-esteem, body image, and quality of life in women with dyspareunia (painful intercourse). Twenty sexually active women aged 18-55 will participate. The goal is to see if this…

This study tests a daily testosterone gel to see if it can safely improve sexual interest and arousal in women going through menopause. Researchers will compare the gel to a placebo in 150 women aged 40-65 who have been diagnosed with low sexual desire. The goal is to provide a m…

This study tests whether a non-surgical radiofrequency device can improve vaginal health and sexual function in postmenopausal women. Forty women aged 40-65 will receive either active treatment or a sham procedure over six weekly sessions. The goal is to see if this approach safe…

This study tests whether a cream containing both testosterone and estrogen works better than estrogen alone to reduce pain during sex for women with vulvodynia. About 44 adult women with moderate to severe pain will use one of the two creams daily. The goal is to find a more effe…

This study uses an online questionnaire to gather information from 15,000 Spanish-speaking adults about their sexual health, behaviors, and any experiences of altered consciousness during orgasm. The goal is to better understand the range of sexual function and pleasure, and to e…

This study examines the most common symptoms of genitourinary syndrome of menopause (GSM) in postmenopausal women and how these symptoms impact quality of life. Researchers will also look at whether using a non-hormonal topical gel called XCM INTIM for at least 8 weeks is linked …

This observational study will examine whether the size and shape of the prostatic urethra and seminal vesicles, as seen on prostate MRI, are linked to premature ejaculation (PE) severity. Researchers will compare 150 men with and without PE, all already scheduled for an MRI. Part…