Sexual disorder

This study tests whether a new drug called BP1.4979 can help men with lifelong premature ejaculation last longer during sex. Sixty men aged 18 to 50 will take either the drug or a placebo before sex for 12 weeks. Researchers will measure ejaculation time and check for side effect…

This study tests a new drug called KH-001, taken as a fast-dissolving tablet under the tongue 15 minutes before sex, to see if it helps men with lifelong premature ejaculation last longer. About 40 men in stable relationships will try the drug or a placebo for 4 weeks each, with …

Endometriosis often causes long-lasting pelvic pain that can disrupt daily life. This trial tests whether specialized pelvic floor physical therapy, combined with a structured exercise program, can lower pain more than a placebo version of the therapy. Women aged 18 to 45 with co…

This study tests whether a vaginal estrogen cream (Imvexxy) can improve sexual function in breastfeeding women who are 6 weeks to 6 months postpartum. About 100 participants will either use the estrogen cream or a placebo-like vitamin E suppository for 12 weeks. The goal is to se…

This study tests if a 12-week cognitive behavioral therapy (CBT) program can help people with paraphilic disorders reduce problematic sexual behaviors and improve their mental health. Researchers will track daily symptoms and interview participants about their experiences. The go…

This study tests three pelvic floor treatments in 150 men with lifelong premature ejaculation: electromagnetic stimulation, biofeedback training, and standard exercises. The goal is to see which best increases ejaculation time and improves control. Participants will be treated fo…

This study tests a vaginal tablet called AZU-101 (lasofoxifene) in 90 postmenopausal women aged 45-60 who have vaginal atrophy, causing dryness and pain during sex. The tablet is given daily for 14 days to see if it is safe and can improve vaginal cell health and lower vaginal pH…

This study tests whether physiotherapy and a special light therapy (photobiomodulation) can reduce pain in women with provoked vestibulodynia, a condition that causes pain during intercourse or tampon use. About 240 Canadian women will receive one of four treatments: light therap…

This study tests a device that uses radiofrequency and ultrasound energy to treat pain during sex caused by scars from vaginal tears or episiotomies after childbirth. About 34 women will receive the treatment and be followed for 1.5 months to see if their pain improves. The goal …

This study tests a new hormone-free gel for women with genitourinary syndrome of menopause (GSM), which causes vaginal dryness, pain, and other symptoms. About 80 postmenopausal women will use the gel for 8 weeks. Researchers will measure changes in quality of life using a questi…

This study tests whether an 8-week pelvic floor exercise program can improve erectile dysfunction and premature ejaculation in men aged 25-45. Half of the 50 participants will do the exercises three times a week, while the other half receives standard medical care. The goal is to…

This study looks at whether adding pelvic floor physical therapy before standard radiation treatment can help reduce pain and sexual problems in women with cervical, vaginal, vulvar, uterine, or anal cancer. About 20 participants will receive education on using a vaginal dilator …

This study tests whether adding hypopressive exercises to standard pelvic floor muscle training helps women aged 45-65 with mild pelvic organ prolapse. About 46 married, postmenopausal women with stage I or II prolapse will be split into two groups: one doing standard exercises a…

This study is testing whether pelvic floor therapy—a mix of exercises, biofeedback, and mild electrical stimulation—can help men with erectile dysfunction and/or premature ejaculation. Sixty-six men will be split into three groups based on their condition and will receive the the…

This study is testing SHAReClinic, a national virtual clinic that provides sexual health education and counselling to prostate cancer patients and their partners. Researchers will enroll 575 people across Canada to see if the program improves sexual function, reduces distress, an…

This study aims to understand how a light-based treatment called photobiomodulation affects sexual quality of life in women with breast cancer who have menopausal symptoms like vaginal dryness and pain. About 25 women will be asked about their sexual health before and after the t…

This study looks at whether a group support program is practical and helpful for female partners of men who have viewed child sexual abuse material. Researchers will check if 15-20 women can be recruited within a year and if they find the program useful. The goal is to understand…

This study aims to find out if chronic pelvic pain conditions like prostatitis and interstitial cystitis can be inherited. Researchers will collect DNA and urine from 500 participants, including family members, to look for genetic links. The goal is to better understand the cause…

This study looks at whether women with Ehlers-Danlos syndrome (EDS) experience more severe period pain than those without the condition. Researchers will compare pain levels and other gynecological issues in 156 women using an online questionnaire. The goal is to better understan…

This study compares 240 people with paraphilic disorders, compulsive sexual behavior, or sexsomnia to healthy controls. Researchers will assess violence history, psychiatric traits, and genetic factors through interviews, questionnaires, and blood samples. The clinical group will…

This study looks at 1,000 women to see how ultrasound features of adenomyosis (a condition where the uterine lining grows into the muscle wall) match up with their symptoms like pain and heavy bleeding. Participants get one routine ultrasound and fill out a symptom questionnaire.…