Middle ear disorder

This study tests a new whole-cell pneumococcal vaccine (wSp) in healthy children aged around 7 to 9 months who already received standard pneumonia vaccines. The goal is to see if wSp reduces pneumococcal bacteria in the nose and boosts immune protection. Researchers will compare …

This study looks at two methods to help doctors prescribe fewer antibiotics for children with ear infections when they aren't needed. One method uses changes to electronic health records and feedback reports for doctors. The other adds a shared decision-making tool that involves …

This study tests a new device that uses artificial intelligence to help diagnose ear infections, strep throat, and asthma flare-ups in children. About 84 kids aged 3 to 17 will either use the device at home with a doctor's video visit or receive standard in-person care. The goal …

This study tests a new device that uses special lights to look at the eardrum and detect fluid behind it, which is a sign of middle ear infection. The goal is to make diagnosis more accurate than current methods. The study will include 150 people of all ages who are scheduled for…

This study tests whether a new imaging technology called optical coherence tomography (OCT) can help doctors more accurately diagnose ear infections in children. Researchers will compare standard ear exams with OCT-enhanced exams in 235 children. The goal is to see if OCT reduces…

This study tests whether an AI-powered app can help doctors more accurately diagnose ear infections in young children (6-24 months) with cold symptoms. Researchers will compare standard ear exams with the AI app's analysis of eardrum photos. The goal is to see if the AI reduces u…

This study tests whether a 20-minute session of passive music therapy, delivered through an app just before entering the operating room, can lower anxiety and pain in adults undergoing ear, nose, or throat surgery. Five hundred participants will be randomly assigned to receive mu…

This study tests whether a new nasal spray system that delivers fluticasone deeper into the nose can relieve Eustachian tube dysfunction (ETD) — a condition causing ear pressure, popping, and muffled hearing. About 80 adults with chronic ETD will receive either the active spray o…

This study tests whether adding Buteyko breathing exercises to a smoking hygiene program can improve Eustachian tube function and lung health in 40 teens who are regularly exposed to secondhand smoke at home. Participants will practice the breathing technique daily for 6 months. …

This study tests whether Buteyko breathing exercises can ease chronic Eustachian tube dysfunction in seniors. Forty older adults with long-term ear blockage will either receive standard care (nasal spray and medication) or standard care plus 30 minutes of Buteyko breathing twice …

This study collects medical information and samples from people with hearing, balance, taste, smell, voice, speech, or language disorders. Researchers aim to use this data for future studies and to find candidates for other research. Participants receive standard care, and no exp…

This large observational registry aims to collect data from over 13,000 adults across Europe with rare head and neck cancers, including cancers of the nasopharynx, nasal cavity, salivary glands, and middle ear. Researchers will track patient outcomes like survival, treatment resp…

This study looks at how often young children get ear infections from RSV, a common virus. Researchers will track 1900 children under 2 years old to see how many have RSV-related ear infections, with or without bronchiolitis. The goal is to better understand the burden of RSV in t…

This study collects a small sample of fluid from the ears of children aged 3 months to 15 years who have a draining ear infection (otorrhea). The goal is to identify which bacteria are present using standard lab tests and newer molecular methods. By understanding the bacterial ca…

This large observational study is checking how pneumococcal vaccines have changed the types of bacteria living in children's noses. Researchers will compare healthy children and those with ear infections to see which bacterial strains are present and whether they resist antibioti…

This study tests whether a two-part approach—improving communication about viral infections and having pharmacists double-check prescription lengths—can reduce how many days antibiotics are prescribed for respiratory infections like bronchitis, sinusitis, and sore throat. About 4…

This study is a registry that will follow 300 children under 18 who receive a balloon dilation treatment for Eustachian tube dysfunction. Researchers will track how often the procedure fails and needs repeat surgery. The goal is to confirm the device's real-world performance in k…

This study looks at how families feel about antibiotic use and whether a Garmin smartwatch can track symptoms in children aged 4-17 with common infections like UTIs, tonsillitis, or skin infections. About 300 children from the Royal Children's Hospital Emergency Department will w…