Middle ear disorder
MONDO:0003276A disease involving the middle ear.
Also known as: disease of middle ear, disease or disorder of middle ear, disorder of middle ear, middle Ear disorder, middle ear disease, middle ear disease or disorder
64 clinical trials for this condition and its sub-types.
Follow this condition — get notified about new trialsSub-types
Broader categories
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New program aims to cut unnecessary antibiotics for kids by training doctors and giving feedback
Disease control OngoingThis study tests whether online training and regular feedback reports can help doctors prescribe fewer antibiotics for common infections like ear infections, strep throat, sinusitis, and pneumonia in children. About 420 children aged 6 months to 12 years are included. The goal is…
Sponsor: Children's Hospital of Philadelphia • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Breakthrough ear tube device could make surgery obsolete for kids
Disease control OngoingThis study tests a new device called Solo+ that places tiny tubes in the eardrums of children with ear infections. The goal is to see if it is safe and effective when done in a doctor's office instead of an operating room. About 66 children aged 6 months to 12 years will be enrol…
Phase: NA • Sponsor: AventaMed DAC • Aim: Disease control
Last updated Jun 27, 2026 12:01 UTC
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Can a probiotic shield kids from antibiotic side effects?
Disease control OngoingThis study tests whether giving a probiotic (Saccharomyces boulardii) along with a common antibiotic can protect the gut bacteria of children aged 4 to 12 being treated for ear or sinus infections. The goal is to see if it reduces antibiotic-associated diarrhea and limits the spr…
Phase: PHASE4 • Sponsor: Eskisehir Osmangazi University • Aim: Disease control
Last updated Jun 27, 2026 08:09 UTC
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Ear injury diagnosis showdown: which grading system wins?
Diagnosis ENROLLING_BY_INVITATIONThis study tests how accurately doctors, nurses, and technicians can diagnose ear barotrauma (pressure injury to the ear) using two different grading systems: the TEED score and the O'Neill Grading System (OGS). Thirty healthcare providers will grade 120 photos of eardrums to see…
Sponsor: Northwell Health • Aim: Diagnosis
Last updated Jun 27, 2026 13:08 UTC
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New digital ear scope aims to slash unnecessary antibiotics in children
Diagnosis OngoingThis study compares a digital otoscope (a high-tech ear scope) to a standard one for diagnosing ear infections in young children. Four pediatric clinics in Massachusetts will take part, with two using the digital device and two using the usual scope. The goal is to see if the dig…
Phase: NA • Sponsor: Boston Children's Hospital • Aim: Diagnosis
Last updated Jun 27, 2026 12:37 UTC
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New ear scanner could slash unnecessary antibiotics in kids
Diagnosis OngoingThis study tests a device called OtoSight that helps doctors see inside a child's ear more clearly. The goal is to see if using it leads to fewer unnecessary antibiotic prescriptions, better outcomes, and lower costs. About 700 children aged 6 months to 17 years with ear pain are…
Sponsor: PhotoniCare, Inc. • Aim: Diagnosis
Last updated Jun 27, 2026 12:32 UTC
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New ultrasound otoscope aims to spot ear infections with greater accuracy
Diagnosis OngoingThis study tests an advanced ultrasound otoscope, a device that uses sound waves to look inside the ear and detect fluid behind the eardrum. Researchers will compare its readings to the surgeon's findings during ear tube surgery in 300 children up to 12 years old. The goal is to …
Sponsor: Baylor College of Medicine • Aim: Diagnosis
Last updated Jun 26, 2026 16:37 UTC
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Nerve block may cut opioid use in Kids' ear surgery
Symptom relief TerminatedThis study tests whether adding a superficial cervical plexus block to standard care reduces opioid use and pain in children aged 3 months to 18 years undergoing ear surgery (cochlear implant or tympanomastoidectomy). Half the children get the block plus standard care, the other …
Phase: PHASE4 • Sponsor: University of Minnesota • Aim: Symptom relief
Last updated Jun 27, 2026 13:00 UTC
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Bioactive glass could ease ear surgery After-Effects
Symptom relief ENROLLING_BY_INVITATIONThis study tests whether using bioactive glass granules during a second ear surgery can improve quality of life for people with ongoing problems like discharge, dizziness, or trouble using hearing aids. Fifty adults who had prior ear surgery will receive the procedure and be foll…
Sponsor: Azienda Socio Sanitaria Territoriale Ovest Milanese, Ospedale di Legnano • Aim: Symptom relief
Last updated Jun 27, 2026 12:04 UTC
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New ear tube position may reduce surgery risks for kids
Symptom relief OngoingThis study looks at where ear tubes are placed in children with ear infections. Normally, tubes go in the front part of the eardrum, but this trial places them in the back part in one ear to see if it lowers the risk of a hole that won't heal. About 386 children will be followed …
Phase: NA • Sponsor: David Chi, MD • Aim: Symptom relief
Last updated Jun 27, 2026 09:07 UTC
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Massive study aims to curb unnecessary antibiotics in kids
Knowledge-focused OngoingThis project works to make sure children with common respiratory infections get the right antibiotics for the right amount of time. It involves over 259,000 kids across many clinics. The goal is to learn the best ways to help doctors follow antibiotic guidelines and reduce unnece…
Sponsor: Intermountain Health Care, Inc. • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:00 UTC
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French ear infection questionnaire study pulled before it began
Knowledge-focused TerminatedThis study aimed to translate and validate a French version of the COMQ-12 questionnaire, which measures quality of life in children with chronic otitis media (ongoing ear infections). Researchers planned to have children aged 7 to 15 with and without ear infections fill out the …
Sponsor: Assistance Publique - Hôpitaux de Paris • Aim: Knowledge-focused
Last updated Jun 27, 2026 07:51 UTC